Therapeutic effects of flap operation on treating severe periodontitis and influence of it on inflammatory factors

摘要

Objective: To investigate therapeutic effects of Widman flap operation on treating severechronic periodontitis and influence of it on inflammatory factors. Methods: A total of 129cases of patients with severe chronic periodontitis treated in the dental department of ourhospital from Nov2014 to Mar2016 were selected as investigate subjects. They were randomlydivided to be 63 cases of control group and 66 cases of observation group. For control group,basic treatment was provided. For observation group, improved Widman flap operationwas provided. Compared with the effects between two groups of patients, and analyzed thevariation of each inflammatory factor before and after treatment. Results: Before treatment, nosignificant difference showed on PLI, SBI, CAL, PD indexes between two groups of patients.6 weeks after treatment, PLI, SBI, PD in observation group were significantly decreasedcomparing with prior treatment, and PLI, SBI were significantly lower than control group atthe same phase. 12 weeks after treatment, PLI in control group were significantly decreasedcomparing with prior treatment; PLI, SBI, CAL, PD in observation group were significantlydecreased comparing with prior treatment, and were significantly lower than control group atthe same phase. Before treatment, no significant difference showed on IL-1毬, IL-6, TNF-毩,CRP levels between two groups of patients. After treatment, 4 inflammatory factors in controlgroup showed no significant variation comparing with the same group before treatment, 4inflammatory factor levels in observation group were significantly lower than which beforetreatment, IL-1毬, IL-6, TNF-毩 were significantly lower than control group at the same phase.Conclusion: Improving extent of modified Widman flap operation to periodontal indexes andinflammatory factors in patients with severe periodontitis were better than the basic treatmentfor control group. It could be a choice for treatment of severe periodontitis.