Therapeutic effects of flap operation on treating severe periodontitis and influence of it on inflammatory factors

摘要

Objective:To investigate therapeutic effects of Widman flap operation on treating severe chronic periodontitis and influence of it on inflammatory factors.Methods:A total of 129 cases of patients with severe chronic periodontitis treated in the dental department of our hospital from Nov2014 to Mar2016 were selected as investigate subjects. They were randomly divided to be 63 cases of control group and 66 cases of observation group. For control group, basic treatment was provided. For observation group, improved Widman flap operation was provided. Compared with the effects between two groups of patients, and analyzed the variation of each inflammatory factor before and after treatment.Results:Before treatment, no significant difference showed on PLI, SBI, CAL, PD indexes between two groups of patients. 6 weeks after treatment, PLI, SBI, PD in observation group were significantly decreased comparing with prior treatment, and PLI, SBI were significantly lower than control group at the same phase. 12 weeks after treatment, PLI in control group were significantly decreased comparing with prior treatment;PLI, SBI, CAL, PD in observation group were significantly decreased comparing with prior treatment, and were significantly lower than control group at the same phase. Before treatment, no significant difference showed on IL-1β, IL-6, TNF-α, CRP levels between two groups of patients. After treatment, 4 inflammatory factors in control group showed no significant variation comparing with the same group before treatment, 4 inflammatory factor levels in observation group were significantly lower than which before treatment, IL-1β, IL-6, TNF-α were significantly lower than control group at the same phase. Conclusion:Improving extent of modified Widman flap operation to periodontal indexes and inflammatory factors in patients with severe periodontitis were better than the basic treatment for control group. It could be a choice for treatment of severe periodontitis.