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Helicopter EMS and rapid transport for ST-elevation myocardial infarction: The HEARTS study

机译:直升机EMS和快速运输治疗ST抬高型心肌梗塞:HEARTS研究

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Background: Helicopter emergency medical services (HEMS) and ground EMS (GEMS) are both integral parts of out-of-hospital transport systems for patients with ST-elevation myocardial infarction (STEMI) undergoing emergency transport for primary percutaneous coronary intervention (PPCI). There are firm data linking time savings for PPCI transports with improved outcome. A previous pilot analysis generated preliminary estimates for potential HEMS-associated time savings for PPCI transports. Methods: This non-interventional multicenter study conducted over the period 2012–2014 at six centers in the USA and in the State of Qatar assessed a consecutive series of HEMS transports for PPCI; at one center, consecutive GEMS transports of at least 15 miles were also assessed if they came from sites that also used HEMS (dual-mode referring hospitals). The study assessed time from ground or air EMS dispatch to transport a patient to a cardiac center, through to the time of patient arrival at the receiving cardiac unit, to determine proportions of patients arriving within accepted 90- and 120-minute time windows for PPCI. Actual times were compared to “route-mapping” GEMS times generated using geographical information software. HEMS' potential time savings were calculated using program-specific aircraft characteristics, and the potential time savings for HEMS was translated into estimated mortality benefit. Results: The study included 257 HEMS and 27 GEMS cases. HEMS cases had a high rate of overall transport time (from dispatch to receiving cardiac unit arrival) that fell within the predefined windows of 90 minutes (67.7% of HEMS cases) and 120 minutes (91.1% of HEMS cases). As compared to the calculated GEMS times, HEMS was estimated to accrue a median time saving of 32 minutes (interquartile range, 17–46). The number needed to transport for HEMS to get one additional case to PPCI within 90 minutes was 3. In the varied contexts of this multicenter study, the number of lives saved by HEMS, solely through time savings, was calculated as 1.34 per 100 HEMS PPCI transports. Conclusions: In this multicenter study, HEMS PPCI transport was found to be appropriate as defined by meeting predefined time windows. The overall estimate for lives saved through time savings alone was consistent with previous pilot data and was also generally consistent with favorable cost-effectiveness. Further research is necessary to confirm these findings, but judicious HEMS deployment for PPCI transports is justified by these data.
机译:背景:直升机急诊医疗服务(HEMS)和地面急诊服务(GEMS)都是ST抬高型心肌梗死(STEMI)接受急诊转运以进行初次经皮冠状动脉介入治疗(PPCI)的患者的院外转运系统的组成部分。可靠的数据链接节省了PPCI传输的时间,并提高了结果。先前的先导分析为PPCI传输可能节省的HEMS相关时间产生了初步估计。方法:这项非干预性多中心研究于2012年至2014年期间在美国和卡塔尔州的六个中心进行,评估了PMS的一系列连续HEMS转运;在一个中心,如果来自同样使用HEMS(双模转诊医院)的站点,也对至少15英里的GEMS连续运输进行了评估。该研究评估了从地面或空中EMS派遣到将患者运送到心脏中心直到患者到达心脏接收单元的时间,以确定在可接受的PPCI 90分钟和120分钟时间范围内到达患者的比例。将实际时间与使用地理信息软件生成的“路线映射” GEMS时间进行了比较。 HEMS的潜在时间节省是使用特定于计划的飞机特性来计算的,并将HEMS的潜在时间节省转换为估计的死亡率收益。结果:该研究包括257例HEMS和27例GEMS。 HEMS病例的总体运输时间(从调度到接收心脏单元到达)的比率很高,落在预定义的90分钟(占HEMS病例的67.7%)和120分钟(占HEMS病例的91.1%)之内。与计算出的GEMS时间相比,估计HEMS平均可节省32分钟的时间(四分位间距为17-46)。在90分钟之内运送HEMS到PPCI的另外一个病例所需的运输数量是3。在此多中心研究的不同背景下,仅通过节省时间,HEMS所挽救的生命数量就计算为每100 HEMS PPCI 1.34运输。结论:在这项多中心研究中,通过满足预定义的时间窗口,发现HEMS PPCI传输是合适的。仅通过节省时间就可以挽救生命的总体估算与先前的试验数据相符,并且总体上也与良好的成本效益相符。需要进一步的研究来证实这些发现,但是这些数据证明了为PPCI传输明智地部署HEMS是合理的。

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