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Osteoarthritis: pathophysiology and current treatment modalities

机译:骨关节炎:病理生理和当前治疗方式

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Osteoarthritis (OA) is accepted as a major public health problem. It is one of the major causes of impaired function that reduces quality of life (QOL) worldwide. OA is a very common disorder affecting the joint cartilage. As there is no cure for OA, treatments currently focus on management of symptoms. Pain relief, improved joint function, and joint stability are the main goals of therapy. The muscle weakness and muscle atrophy contribute to the disease process. So, rehabilitation and physiotherapy were often prescribed with the intention to alleviate pain and increase mobility. However, as exercise has to be performed on a regular basis in order to counteract muscle atrophy, continuous exercise programs is recommended in people with degenerative joint disease. Therapeutic exercise regimes either focus on muscle strengthening and stretching exercises or on aerobic activity which can be land or water based. This article presents on overview of the current knowledge on OA and focuses on biomechanics, etiology, diagnosis and treatment strategies, conservative treatment including the physical therapy management are discussed. This information should assist health care practioners who treat patients with this disorder.
机译:骨关节炎(OA)被认为是主要的公共卫生问题。这是功能受损导致世界范围内生活质量(QOL)下降的主要原因之一。 OA是一种非常常见的影响关节软骨的疾病。由于无法治愈OA,因此目前的治疗重点是症状的管理。缓解疼痛,改善关节功能和关节稳定性是治疗的主要目标。肌肉无力和肌肉萎缩有助于疾病的发展。因此,经常开处方进行康复和物理治疗,以减轻疼痛和增加活动能力。但是,由于必须定期进行运动以抵消肌肉萎缩,因此建议在患有退行性关节病的患者中进行连续运动。治疗性运动方案要么集中于肌肉增强和伸展运动,要么着重于有氧运动,这些运动可以基于陆地或水。本文概述了有关OA的当前知识,并重点介绍了生物力学,病因,诊断和治疗策略,并讨论了包括物理疗法管理在内的保守治疗。该信息应有助于治疗患有该疾病的患者的医疗保健从业者。

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