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An Overview on Transdermal Drug Delivery System

机译:透皮给药系统概述

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Transdermal drug delivery is involved in the transportation of drug through the skin for systemic circulation. Now a day’s more than 74% of drugs are administered drug in the form of tablet, capsule, which are taken orally but sometimes those are not effective as desired due to physiological activities of body. The major obstruction caused by stratum corneum to penetrate the drug. So there is need to facilitate the stratum corneum to increase the flux, a number of approaches are used to enhance the penetration of drug. Transdermal drug delivery system (TDDS) are very effectively overcome the hepatic first pass metabolism and improve the steady plasma drug concentration. The present review article provides an overview of various types of transedrmal patches, method of preparation and their evaluation.
机译:透皮药物输送涉及药物通过皮肤输送以进行全身循环。如今,每天有超过74%的药物以片剂,胶囊剂的形式口服,但由于身体的生理活动,有时效果不佳。由角质层穿透药物引起的主要阻塞。因此,需要促进角质层以增加通量,许多方法被用于增强药物的渗透。透皮给药系统(TDDS)非常有效地克服了肝首过代谢并提高了稳定的血浆药物浓度。本综述文章概述了各种类型的经皮贴剂,制备方法及其评估。

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