Systemic chemotherapy alone for Langerhans cell histiocytosis in the mandibular condyle with preservation of the alveolar bone

摘要

Langerhans cell histiocytosis (LCH) is a rare disease with unknown pathogenesis. According to the characteristics of the illness, LCH can be divided into three clinical forms: eosinophilic granuloma, Hand-Schüller-Christian disease, and Letterer-Siwe disease. In 1953, Lichtenstein found the common lesional histiocyte-like cell X in the histological section of LCH, and he collectively named these diseases “histiocytosis X” (X represents its unknown etiological factor).1 Then, the lesional histiocyte-like cell X was found to be the Langerhans cell; therefore, the disease was renamed Langerhans cell histiocytosis.2.