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Non-sequential and non-stimulated bilateral adrenal vein sampling utility in primary aldosteronism: Case inform

机译:非序贯性和非刺激性双侧肾上腺静脉采样在原发性醛固酮增多症中的作用:病例信息

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PurposeTo present a case of a 20-year-old Mexican woman with resistant high blood pressure and the procedures the medical staff underwent to identify the etiology of her illness, as well as the choice of treatment.Material and methodsWe present a case of a 20-year-old Mexican woman, who showed up to the emergency department at the Military Central Hospital of SEDENA, with decreased visual acuity, persistent headache, and high blood pressure. Her vital signs were a blood pressure of 220/120?mmHg, heart rate of 73 beats per minute, and a respiratory rate of 16 breaths per minute. An electrocardiogram was made and showed hypertrophy of the left cavities. The medical staff sent complementary studies that consisted of a renal ultrasound that showed a right and left kidney with regular dimensions and no signs of stenosis in both renal arteries. The hormonal reports of plasma renin activity were 1.06 ng/ml/h and plasma aldosterone concentration of 30 ng/dL. Plasma aldosterone/renin ratio (ARR) of 28.3 suggested a case of primary aldosteronism (PA).ResultsA simple and contrasted computed tomography of the adrenal glands was performed, which reported normal adrenal glands, without identifying focal lesions. Therefore, it was indicated an adrenal catheterization procedure using a non-sequential and non-stimulating technique to expose unilateral primary aldosteronism.ConclusionsUnilateral adrenalectomy is the cure or means of improvement of the clinical signs and symptoms of patients with unilateral primary aldosteronism, we suggest every PA should undergo an adrenal vein sampling seeking lateralization even thought a CT scan shows no evidence of lesions in the adrenal glands. Further investigation of the effects of medical or surgical treatment on the quality of life of Mexican patients with PA is needed.
机译:目的提出一例20岁的墨西哥妇女耐高血压的病例,以及医务人员进行的识别病因的程序以及治疗方法的选择。材料和方法我们介绍了20例病例。岁的墨西哥女性,在SEDENA军事中心医院的急诊室就诊,视力下降,持续性头痛和高血压。她的生命体征是血压为220 / 120mmHg,心律为每分钟73次,呼吸频率为每分钟16次。进行心电图检查,显示左腔肥大。医务人员进行了补充研究,其中包括肾脏超声检查,该肾脏超声检查显示左右肾脏的大小均正常,并且两条肾动脉均无狭窄迹象。激素报告血浆肾素活性为1.06 ng / ml / h,血浆醛固酮浓度为30 ng / dL。血浆醛固酮/肾素比率(ARR)为28.3表示一例原发性醛固酮增多症(PA)。结果对肾上腺进行了简单而对照的CT扫描,报告的肾上腺正常,未发现病灶。因此,这表明使用非序贯和非刺激性技术进行肾上腺导管插入术可暴露单侧原发性醛固酮增多症。结论单侧肾上腺切除术是治愈或改善单侧原发性醛固酮增多症患者的临床体征和症状的方法。即使认为CT扫描未显示肾上腺有病变的证据,PA也应接受肾上腺静脉采样以寻求侧向化。有必要进一步研究医学或手术治疗对墨西哥PA患者生活质量的影响。

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