The comparison of effects of intrathecal two different levobupivacaine doses in appendectomy

摘要

Objectives:Spinal anesthesia, especially in the pres-ence of coexisting diseases is preferred to reduce mor-bidity and mortality in many surgical practices. In this study, we aimed to compare the motor and sensory block characteristics, hemodynamic parameters, side effects and surgical and patient comfort, whom underwent ap-pendectomy with spinal anesthesia in two different doses of levobupivacaine.Material and methods:After Minister of Health ethical committee approval and written consent of the patients who underwent open appendectomy were obtained, fifhty patients between the ages of 18-40 with ASA I-II were en-rolled in this study. The patients were randomly allocated to two groups; Group I received 15 mg levobupivacaine 0.5% (total 3 ml) and Group II received 20 mg levobupi-vacaine 0.5% (total 4 ml Hemodynamic data, surgical and patient comfort and side effects were also recorded.Results:There were statistically significant differences between the two groups for two segment regression time of sensory block. Two-segment regression time was lon-ger the Group II than Group I. In Group II motor block regression time (Group I 120 ± 40 min, Group II 158 ± 54 min) was significantly longer (p= p<0.05). There were statistically significant difference in numbers of side ef-fects (hypotension, bradicardia) in Group II than Group I (p<0.05).Conclusions:This study showed that 15 mg levobupiva-caine dose provides safe and effective anesthesia for ap-pendectomy surgery