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A Child with Ulcerative Colitis - A Case Report

机译:儿童溃疡性结肠炎-病例报告

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Ulcerative colitis in children has not been reported previouslyin Bangladesh. This case report is of a 7 year old girl whopresented with frequent passage of slimy stool mixed with bloodfor 4 months. She also had fever, weight loss, abdominal painand urgency at defecation. Barium enema showed pancolitiswith multiple pseudopolyps and collar button appearance.Colonoscopy revealed a friable and granular mucosa withdiffuse ulceration and multiple pseudopolyps. There was bloodyexudate and the lumen was narrow. Histopathology findingsshowed necrosed tissue probably representing a base of ulcerand inflammatory cell infiltrate in the lamina propria. Thecrypt architecture was distorted with cryptitis and goblet celldepletion. There was no granuloma. She was diagnosed as acase of ulcerative colitis & treated with Sulfasalazine and oralcorticosteroid. Her response to treatment was very well andnow she is on regular follow up.DOI: 10.3329/jbcps.v28i2.5372J Bangladesh Coll Phys Surg 2010; 28: 117-120
机译:孟加拉国以前没有儿童溃疡性结肠炎的报道。该病例报告是一名7岁女孩,她经常出现粘液便和血液混合4个月。她还发烧,体重减轻,腹痛和排便紧迫。钡剂灌肠表现为全结肠炎,有多个假性息肉和衣领纽的外观;结肠镜检查显示脆性和颗粒状的粘膜,弥漫性溃疡和多个假性息肉有渗出液,管腔狭窄。组织病理学结果显示坏死组织可能代表固有层溃疡和炎性细胞浸润的基础。隐窝炎和杯状细胞耗竭扭曲了隐窝结构。没有肉芽肿。她被诊断为溃疡性结肠炎,并接受柳氮磺吡啶和口服糖皮质激素治疗。她对治疗的反应非常好,现在正在定期随访。DOI:10.3329 / jbcps.v28i2.5372J Bangladesh Coll Phys Surg 2010; 28:117-120

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