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Assessment of Colour Blindness and Erythrocyte G6PD Enzyme Status among the School Children of Dhaka City

机译:达卡市学龄儿童的色盲和红细胞G6PD酶状态评估

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Visual impairment due to colour blindness is an unusual suffering of the school children. It may be associated with erythrocyte G6PD enzyme deficiency. Objective: To find out defective vision due to colour blindness in apparently healthy school children and to measure erythrocyte G6PD enzyme level among them. Methods: This cross sectional study was carried out in the Department of Physiology, SSMC from 1st July 2007 to 31st June 2008. Five hundred (500) apparently healthy school children of old Dhaka, age ranged from 6 to 12 years irrespective of gender and race was selected as study population. Colour vision test was done by Ishihara's test. Erythrocyte G6PD enzyme was measured among the colour blind children. All the results were compared to that of children with normal colour vision. Results: Five male children were detected to have partial red-green type of colour blindness. The percentage of colour blindness was statistically not significant (p>0.05) when compared to that of children with normal colour vision. Mean erythrocyte G6PD enzyme level of colour blind children was significantly lower (p<0.05) compared to that of children with normal colour vision. Presence of G6PD enzyme deficiency among the colour blind children did not show any clinical abnormalities might be due to different non symptomatic G6PD variants. Conclusion: Visual defect due to colour which blindness particularly red-green type might be present in apparently healthy school children associated with erythrocyte G6PD enzyme deficiency. Key words: Colour blindness; Erythrocyte G6PD enzyme. DOI: 10.3329/jbsp.v4i2.4175 J Bangladesh Soc Physiol. 2009 Dec;4(2): 64-70
机译:色盲造成的视力障碍是学童的不正常痛苦。它可能与红细胞G6PD酶缺乏有关。目的:发现明显健康的学龄儿童因色盲导致的视力障碍,并测量其中的红细胞G6PD酶水平。方法:这项横断面研究于2007年7月1日至2008年6月31日在SSMC生理学系进行。显然,达卡(Dhaka)的五百(500)名健康儿童年龄在6至12岁之间,不论性别和种族被选为研究人群。色觉测试是由Ishihara的测试完成的。测定了色盲儿童中的红细胞G6PD酶。将所有结果与色觉正常的儿童进行比较。结果:检测到5名男童患有部分红绿色类型的色盲。与色觉正常的儿童相比,色盲的百分比在统计学上不显着(p> 0.05)。与色觉正常的儿童相比,色盲儿童的平均红细胞G6PD酶水平显着降低(p <0.05)。色盲儿童中G6PD酶缺乏症的存在未显示任何临床异常,可能是由于不同的非症状性G6PD变异引起的。结论:明显健康的学龄儿童伴有红细胞G6PD酶缺乏症,可能是由颜色引起的视觉缺陷,特别是红绿色。关键词:色盲红细胞G6PD酶。 DOI:10.3329 / jbsp.v4i2.4175 J Bangladesh Soc Physiol。 2009年12月; 4(2):64-70

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