Baculovirus Coinfection Strategy for Improved Galactosylation of Recombinant Glycoprotein Produced by Insect Cell Culture

Yap Wei Ney; Badarulhisam Abdul Rahman; Azila Abdul Aziz

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Baculovirus Coinfection Strategy for Improved Galactosylation of Recombinant Glycoprotein Produced by Insect Cell Culture

机译：杆状病毒共感染策略，用于改进昆虫细胞培养产生的重组糖蛋白的半乳糖基化

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Baculovirus Expression Vector System (BEVS) is widely used for the production of recombinant glycoproteins, but it is not ideal for pharmaceutical glycoprotein production due to incomplete glycosylation. The factors that ensure successful glycosylation ar

机译：杆状病毒表达载体系统（BEVS）被广泛用于重组糖蛋白的生产，但由于糖基化不完全，因此不适用于药物糖蛋白的生产。确保成功糖基化的因素

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《Journal of Applied Sciences》 |2007年第15期|共6页
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Yap Wei Ney; Badarulhisam Abdul Rahman; Azila Abdul Aziz;
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1. Expression of a membrane-bound form of Trypanosoma cruzi trans-sialidase in baculovirus-infected insect cells: a potential tool for sialylation of glycoproteins produced in the baculovirus-insect cells system. [J] . Marchal I, Cerutti M, Mir AM, Glycobiology. . 2001,第7期

机译：杆状病毒感染的昆虫细胞中膜结合形式的克氏锥虫转唾液酸酶的表达：杆状病毒-昆虫细胞系统中产生的糖蛋白唾液酸化的潜在工具。
2. Two-dimensional high performance liquid chromatography mapping of sugar chains demonstrated the biantennary, complex N-glycan addition to the recombinant glycoprotein produced by baculovirus-lnfected Antheraea pernyi insect cells [J] . Masahiro Nagaya, Jun Kobayashi, Noriko Takahashi, Journal of insect biotechnology and sericology . 2003,第2期

机译：糖链的二维高效液相色谱图显示，双杆状，复杂的N-聚糖可添加到杆状病毒感染的ther蚕花椰菜昆虫细胞产生的重组糖蛋白中
3. Two-dimensional high performance liquid chromatography mapping of sugar chains demonstrated the biantennary, complex N-glycan addition to the recombinant glycoprotein produced by baculovirus-lnfected Antheraea pernyi insect cells [J] . Masahiro Nagaya, Jun Kobayashi, Noriko Takahashi, Journal of insect biotechnology and sericology . 2003,第2期

机译：糖链的二维高效液相色谱图显示，双杆状，复杂的N-聚糖可添加到杆状病毒感染的ther蚕花椰菜昆虫细胞产生的重组糖蛋白中
4. STUDIES OF PASSAGE EFFECT OF HaNPV BACULOVIRUS PRODUCED IN Hz INSECT CELL CULTURE [C] . Kanokwan Poomputsa, Kultida Poltawee, Somkiet Techkarnjanarak, Annual Meeting of the Japanese Association for Animal Cell Technology . 2006

机译：HANPV杆菌病毒在HZ昆虫细胞培养中产生的研究
5. Creation of a recombinant baculovirus system for expression of the phosphorylase b kinase holoenzyme and the alpha-gamma-delta and gamma-delta subcomplexes in cultured insect cells: Purification and characterization of expressed complexes. [D] . Brushia, Robert Joseph. 1999

机译：创建重组杆状病毒系统以在培养的昆虫细胞中表达磷酸化酶b激酶全酶以及α-γ-δ和γ-δ亚复合物：纯化和表征表达的复合物。
6. Producing Recombinant Adeno-Associated Virus in Foster Cells: Overcoming Production Limitations Using a Baculovirus–Insect Cell Expression Strategy [O] . Tamas Virag, Sylvain Cecchini, Robert M. Kotin -1

机译：在寄养细胞中生产重组腺相关病毒：使用杆状病毒-昆虫细胞表达策略克服生产限制
7. Baculovirus coinfection strategy for improved galactosylation of recombinant glycoprotein produced by insect cell culture [O] . Yap Wei Ney, Abdul Rahman Badarulhisam, Abdul Aziz Azila 2005

机译：杆状病毒共感染策略可改善昆虫细胞培养产生的重组糖蛋白的半乳糖基化

Baculovirus Coinfection Strategy for Improved Galactosylation of Recombinant Glycoprotein Produced by Insect Cell Culture

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