Effect of cold stress on infanticide by female Swiss albino mice Mus musculus : a pilot study

摘要

Mice are widely accepted research models of great clinical significance. Maintenance of laboratory mice breed is an essential aspect for performing research activities in various fields of science. Infanticide is one of the prominent causes of litter loss during maintenance of laboratory mice stock. The present study is an effort to monitor the effect of change in ambient temperature of female mice below the normal range on cannibalism and infanticide during early postparturition phase. Adult female Swiss albino mice have been divided into two groups of control and treatment. On the day of litter group one was maintained under controlled temperature conditions (minimum 20?°C to maximum 23?°C) throughout, while female mice belong to group two have been exposed to variation of room temperature (maximum 15?°C to minimum 10?°C for two nights and one day) until 36?h postparturition. The effects of temperature changes were observed on the infanticide behaviour of dams along with the survival of pups in early postparturition phase till 36?h after delivery. The significant statistical difference (P?