Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection

Dmitriy Zamarin; Rikke Holmgaard; Sumit Subudhi; Mena Mansour; Peter Palese; Taha Merghoub; Jedd D Wolchok; James P Allison

首页> 外文期刊>Journal for ImmunoTherapy of Cancer >Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection

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Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection

机译：局部溶瘤病毒疗法会发炎远处的肿瘤，并与免疫检查点封锁协同作用，导致全身性肿瘤排斥

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《Journal for ImmunoTherapy of Cancer》 |2013年第s1期|共页
作者
Dmitriy Zamarin; Rikke Holmgaard; Sumit Subudhi; Mena Mansour; Peter Palese; Taha Merghoub; Jedd D Wolchok; James P Allison;
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中图分类肿瘤学;
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1. Immune checkpoint blockade can synergize with radiation therapy, even in tumors resistant to checkpoint monotherapy [J] . Digambar Tukaram Shirke, Shashikant Kuber Khilarea, Jan D?rrie EMBO Molecular Medicine . 2016,第2期

机译：免疫检查点阻滞可以与放射疗法协同作用，即使在对检查点单一疗法有抵抗力的肿瘤中也是如此
2. Activation of the cytosolic RNA receptor RIG-I in tumor and immune cells triggers efficient anti-tumor immunity and synergizes with checkpoint blockade [J] . Heidegger S., Alexander W., Kreppel D., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2016,第Suppla1期

机译：在肿瘤和免疫细胞中激活细胞溶质RNA受体钻井液I触发有效的抗肿瘤免疫力，并通过检查点封闭来协同增长
3. 132?CAR macrophages (CAR-M) elicit a systemic anti-tumor immune response and synergize with PD1 blockade in immunocompetent mouse models of HER2 solid tumors [J] . Stefano Pierini, Rashid Gabbasov, Linara Gabitova, Journal for ImmunoTherapy of Cancer . 2020,第Suppla3期

机译：132克巨噬细胞（CAR-M）引发全身抗肿瘤免疫应答，并用PD1封闭在HER2固体瘤的免疫活性小鼠模型中得到协同作用
4. Microtubule-Depolymerizing Agents Used in ADCs Induce Anti-Tumor Immunity and Synergize with Immune Checkpoint Blocking Antibodies [C] . Philipp Muller, Kea Martin, Sebastian Theurich, PEGS . 2014

机译：ADCS中使用的微管 - 解聚剂诱导抗肿瘤免疫，并用免疫检查点阻断抗体进行协同
5. Multilevel Targeting of Canine Adenovirus Type 2 (CAV2) to Expand Oncolytic Virotherapy in Canine Tumors [D] . Sajib, Abdul Mohin. 2020

机译：犬腺病毒2（CAV2）的多级靶向，以扩大犬肿瘤的溶瘤病毒
6. Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection [O] . Dmitriy Zamarin, Rikke Holmgaard, Sumit Subudhi, 2013

机译：局部溶瘤病毒疗法会发炎远处的肿瘤并与免疫检查点封锁协同作用导致全身性肿瘤排斥
7. Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection [O] . 2013

机译：局部溶瘤病毒疗法会发炎远处的肿瘤，并与免疫检查点封锁协同作用，导致全身性肿瘤排斥

Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection

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