CD28 co-stimulation induced Lck signaling is important for survival and antigen-specific functionality of re-directed T cells

Pratiksha Gulati; Petra Schuberth; Christoph Renner; Christian Munz; Ulf Petrausch

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CD28 co-stimulation induced Lck signaling is important for survival and antigen-specific functionality of re-directed T cells

机译：CD28共同刺激诱导的Lck信号对于重定向T细胞的存活和抗原特异性功能很重要

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《Journal for ImmunoTherapy of Cancer》 |2013年第s1期|共页
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Pratiksha Gulati; Petra Schuberth; Christoph Renner; Christian Munz; Ulf Petrausch;
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中图分类肿瘤学;
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1. Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice [J] . Gulati Pratiksha, Ruhl Julia, Kannan Abhilash, Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第16期

机译：异常的LCK信号通过CD28共染色增强抗原特异性功能和肿瘤对通过人源化小鼠的PD-1阻断的重定向的T细胞进行肿瘤控制
2. T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses [J] . Einar?M. Aandahl, Kjetil Taskén, Kristine Moltu, The biochemical journal . 2014,第3期

机译：通过CD2和CD28共受体的T细胞共刺激诱导不同的信号传导反应
3. MHC class I cross-talk with CD2 and CD28 induces specific intracellular signalling and leads to growth retardation and apoptosis via a p56(lck)-dependent mechanism. [J] . Ruhwald M, Pedersen AE, Claesson MH Experimental and Clinical Immunogenetics . 1999,第4期

机译：与CD2和CD28的MHC I类串扰诱导特定的细胞内信号传导，并通过p56（lck）依赖性机制导致生长迟缓和凋亡。
4. Notch and T Cell Receptor Signaling through Biomaterials for Generating Functional, Antigen-Specific T cells from Stem Cells [C] . Mvung Hee Kim, Tracy Ooi, Irina Fernandez, Society for Biomaterials fall symposium 2012.;vol. 34. . 2012

机译：Notch和T细胞受体信号传导通过生物材料从干细胞中生成功能性，抗原特异性T细胞
5. CD28-Mediated Pro-Survival Signaling: A Novel Therapeutic Target for the Treatment of Multiple Myeloma [D] . Murray, Megan Elizabeth 2015

机译：CD28介导的生存前信号：一种新型的治疗靶点治疗多发性骨髓瘤。
6. CD28 co-stimulation induced Lck signaling is important for survival and antigen-specific functionality of re-directed T cells [O] . Pratiksha Gulati, Petra Schuberth, Christoph Renner, 2013

机译：CD28共刺激诱导的Lck信号对于重定向T细胞的存活和抗原特异性功能很重要
7. CD28 co-stimulation induced Lck signaling is important for survival and antigen-specific functionality of re-directed T cells [O] . Pratiksha Gulati, Petra Schuberth, Christoph Renner, 2013

机译：CD28共刺激诱导的Lck信号对于重定向T细胞的存活和抗原特异性功能很重要
8. CD28 is an Inducible T Cell Surface Antigen that Transduces a Proliferative Signal in CD3(+) Mature Thymocytes. [R] . Turka, L. A., Ledbetter, J. A., Lee, K., 1990

机译：CD28是诱导性T细胞表面抗原，其转导CD3（+）成熟胸腺细胞中的增殖信号。

CD28 co-stimulation induced Lck signaling is important for survival and antigen-specific functionality of re-directed T cells

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