Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy

Hong Jiang; Brett Knolhoff; Yu Zhu; John Herndon; Irina Shapiro; David Weaver; Jonathan Pachter; Andrea Wang-Gillam; David G DeNardo

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Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy

机译：靶向粘着斑激酶可重编程胰腺肿瘤微环境，并使胰腺癌对检查点免疫疗法有反应

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来源
《Journal for ImmunoTherapy of Cancer》 |2015年第s2期|共页
作者
Hong Jiang; Brett Knolhoff; Yu Zhu; John Herndon; Irina Shapiro; David Weaver; Jonathan Pachter; Andrea Wang-Gillam; David G DeNardo;
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中图分类肿瘤学;
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专利

1. Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy [J] . Jiang Hong, Hegde Samarth, Knolhoff Brett L., Nature medicine . 2016,第8期

机译：靶向粘着斑激酶使胰腺癌对检查点免疫疗法有反应
2. Co-inhibition of the TGF-beta pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy [J] . Wang Yang, Gao Zhuxin, Du Xiaojiao, Biomaterials Science . 2020,第18期

机译：通过pH响应聚类纳米粒子进行TGF-β通路和PD-L1检查点的共抑制胰腺癌微环境调控和抗肿瘤免疫治疗
3. Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment. [J] . Stokes JB, Adair SJ, Slack Davis JK, Molecular cancer therapeutics . 2011,第11期

机译：PF-562,271抑制粘着斑激酶可抑制胰腺癌的生长和转移，同时改变肿瘤的微环境。
4. Focal Adhesion Kinase Expression: A Potential Tumor Therapy Target [C] . Shufeng Li, Wei Dong, Yiwei Zong, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：局灶性黏附激酶表达：潜在的肿瘤治疗目标。
5. Investigation of Phosphorylation and Ligand Binding of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase. [D] . Cable, Jennifer Lynn. 2011

机译：焦粘附激酶的焦粘附靶向域的磷酸化和配体结合研究。
6. Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy [O] . Hong Jiang, Brett Knolhoff, Yu Zhu, 2015

机译：靶向粘着斑激酶可重编程胰腺肿瘤微环境并使胰腺癌对检查点免疫疗法有反应
7. Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy [O] . 2015

机译：靶向粘着斑激酶可重编程胰腺肿瘤微环境，并使胰腺癌对检查点免疫疗法有反应
8. Characterization of the Role of Breast Tumor Kinase (Brk) in Breast Cancer Cells Non-Responsive to EGFR-Targeted Agents [R] . Nimnual, A. S. 2008

机译：不响应EGFR靶向药物表征乳腺癌激酶（Brk）在乳腺癌细胞中的作用

Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy

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