Monoclonal antibodies targeting cell surface deposited complement fragment C3d potentiate cancer immunotherapy and eliminate antigen loss variants

Martin Skarzynski; Margeret Lindorfer; Vicent Butera; Berengere Vire; Mohammed Farooqui; Christoph Rader; Ronald Taylor; Adrian Wiestner

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Monoclonal antibodies targeting cell surface deposited complement fragment C3d potentiate cancer immunotherapy and eliminate antigen loss variants

机译：靶向细胞表面沉积的补体片段C3d的单克隆抗体可增强癌症免疫治疗并消除抗原丢失变异体

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《Journal for ImmunoTherapy of Cancer》 |2015年第s2期|共页
作者
Martin Skarzynski; Margeret Lindorfer; Vicent Butera; Berengere Vire; Mohammed Farooqui; Christoph Rader; Ronald Taylor; Adrian Wiestner;
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中图分类肿瘤学;
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1. Activation of complement by monoclonal antibodies that target cell-associated β2-microglobulin: Implications for cancer immunotherapy [J] . PokrassM.J., LiuM.F., LindorferM.A., Molecular Immunology . 2013,第4期

机译：靶向细胞相关β2-微球蛋白的单克隆抗体激活补体：对癌症免疫治疗的意义
2. Identification of the membrane receptor for the complement fragment C3d by means of a monoclonal antibody. [J] . K Iida, L Nadler, V Nussenzweig The Journal of Experomental Medicine . 1983,第4期

机译：通过单克隆抗体鉴定补体片段C3d的膜受体。
3. Novel Tumor Antigen-Specific Monoclonal Antibody-Based Immunotherapy to Eradicate Both Differentiated Cancer Cells and Cancer-Initiating Cells in Solid Tumors [J] . Sabbatino Francesco, Wang Yangyang, Wang Xinhui, Seminars in Oncology . 2014,第5期

机译：基于新型肿瘤抗原特异性单克隆抗体的免疫疗法，可消除实体瘤中分化的癌细胞和癌症起始细胞
4. Efficient Acquisition of Antigen-Specific Human Monoclonal Antibody by Using Peripheral Blood Mononuclear Cells Immunized In Vitro Efficient Cloning of Human Monoclonal Antibody Gene [C] . Shinei Matsumoto, Makiko Yamashita, Yoshinori Katakura, Annual Meeting of the Japanese Association for Animal Cell Technology . 2009

机译：通过使用在体外克隆人单克隆抗体基因的体外克隆的外周血单核细胞高效采集抗原特异性人单克隆抗体
5. Targeted delivery of antigens to follicular dendritic cells via a monoclonal antibody specific for complement receptor 2 on marginal zone B cells: Dynamics of delivery and applications towards vaccine development. [D] . Whipple, Emily Christine. 2006

机译：通过对边缘B区细胞的补体受体2特异的单克隆抗体，将抗原靶向递送至滤泡树突状细胞：动力学和疫苗开发应用。
6. Monoclonal antibodies targeting cell surface deposited complement fragment C3d potentiate cancer immunotherapy and eliminate antigen loss variants [O] . Martin Skarzynski, Margeret Lindorfer, Vicent Butera, 2015

机译：靶向细胞表面沉积的补体片段C3d的单克隆抗体可增强癌症免疫治疗并消除抗原丢失变异体
7. Monoclonal antibodies targeting cell surface deposited complement fragment C3d potentiate cancer immunotherapy and eliminate antigen loss variants [O] . 2015

机译：靶向细胞表面沉积的补体片段C3d的单克隆抗体可增强癌症免疫治疗并消除抗原丢失变异体
8. Targeted Radioimmunotherapy of Prostate Cancer Using Monoclonal Antibodies to the Extracelluar Domain of Prostate-Specific Membrane Antigen. [R] . Vallabhajosula, S. 2000

机译：使用针对前列腺特异性膜抗原细胞外结构域的单克隆抗体对前列腺癌进行靶向放射免疫治疗。

Monoclonal antibodies targeting cell surface deposited complement fragment C3d potentiate cancer immunotherapy and eliminate antigen loss variants

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