Patents: April 2011

摘要

A Pd(0)Ln?complex, where L is a ligand and?n?= 2, 3 or 4, is prepared by reacting a Pd(II) complex in a solvent with a base and ligand L. Further base, optionally in a solvent, may be added to form the Pd(0)Ln?complex. The pre-formed Pd(0) complex can be prepared on an industrial scale and used as a catalyst in Pd-catalysed cross-coupling reactions. When?n?= 2, the Pd(II) complex may not be [(o-tol)3P]2PdCl2. The Pd(0)Ln?complex may be, for example, Pd[tBu2(p-PhMe2N)P]2?or Pd[tBu2(Np)P]2.