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首页> 外文期刊>Jornal Vascular Brasileiro >Alternative grafts for brachioaxillary hemodialysis access: 1-year comparative results
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Alternative grafts for brachioaxillary hemodialysis access: 1-year comparative results

机译:替代方法用于腋腋血透治疗:1年比较结果

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BACKGROUND: Many chronic renal patients lack autologous veins in the upper limbs suitable for construction of arteriovenous fistulas for hemodialysis. Alternative fistula options for these patients should be evaluated and compared.OBJECTIVE: To compare different types of grafts used for brachioaxillary access in hemodialysis patients in terms of their patency and complication rates.METHOD: Forty-nine patients free from arterial system abnormalities and with no venous options for creation of arteriovenous fistulae in the arm and/or forearm underwent brachioaxillary bypass with implantation of autologous saphenous vein, polytetrafluoroethylene (PTFE), or PROPATEN(r) grafts. Patients were assessed by Doppler ultrasonography at 3, 6, and 12 months after surgery,.RESULTS: The four first saphenous vein grafts had failed by 3 or 6 months after surgery. The autologous saphenous vein group was discontinued at the beginning of the study because of extreme difficulty in achieving puncture and hematoma formation. Failure rates of PTFE and PROPATEN(r) grafts did not differ after 3 (p = 0.559), 6 (p = 0.920), or 12 months (p = 0.514). A log-rank test applied to cumulative survival of grafts at 1 year (0.69 for PTFE, 0.79 for PROPATEN(r)) detected no significant differences (p = 0.938). There were no differences in complications resulting in graft failure between the two types of prosthetic graft.CONCLUSION: Autologous saphenous vein grafts do not appear to be a good option for brachioaxillary hemodialysis access because of difficulties with achieving puncture. Brachioaxillary fistulae constructed using PTFE or PROPATEN(r) grafts exhibited similar patency and complication rates. Further studies with large samples size are warranted to confirm our findings.
机译:背景:许多慢性肾脏病患者的上肢缺乏自体静脉,适合于动静脉瘘的构建以进行血液透析。目的:比较这些透析患者通畅性和并发症发生率的方法,以比较不同类型的用于血液透析患者的臂腋入路的移植物。方法:四十九例患者无动脉系统异常且无在手臂和/或前臂产生动静脉瘘的静脉选择接受了腋腋旁路移植,并植入了自体大隐静脉,聚四氟乙烯(PTFE)或PROPATEN(r)移植物。结果:在术后3、6个月时,第四个隐静脉移植物失败了,分别在术后3、6和12个月通过多普勒超声检查对患者进行了评估。由于开始穿刺和血肿形成的极度困难,自隐性大隐静脉组在研究开始时即被终止。在3(p = 0.559),6(p = 0.920)或12个月(p = 0.514)之后,PTFE和PROPATEN(r)移植物的失败率没有差异。对移植物在1年的累积存活率进行的对数秩检验(PTFE为0.69,PROPATEN(r)为0.79)没有发现显着差异(p = 0.938)。两种假体之间的并发症并没有导致移植失败的结论。结论:自体大隐静脉移植物由于难以穿刺而似乎不是行腋下血液透析的好选择。使用PTFE或PROPATEN(r)移植物构建的肱腋瘘表现出相似的通畅性和并发症发生率。有必要对大量样本进行进一步研究,以证实我们的发现。

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