Phytochemical screening and comparative analysis of antimicrobial activity of root and leaf extracts of Tinospora coridifolia, Phyllanthus niruri and Abrus precatorious, important medicinal plants

摘要

Medicinal plants have been a basic source of antibiotics against a variety of diseases over the years. This study was carried out to investigate the antibacterial and antifungal activities of the ethanolic extracts ofTinospora cordifoliaMiers.andPhyllanthus niruriL. BothP. niruriandAbrus precatoriousL. have more against the pathogenicEscherichia coliand fungiAspergillus nigerandEpidermophyton floccosumby the filter paper disc method. Among the three plant extracts tested,T. cordifolialeaf extract showed maximum zone of inhibition of 24.0 mm against the bacteriaE. coliat the concentration of 100 mg/ml. Extract ofP. niruriexhibited similar inhibition zone against the bacterium, that is, 22.0 mm.A. precatoriusleaf extract showed no inhibition. Increase in the concentration of plant extract increased the zone of inhibition. The root extract ofA. precatoriusshowed significant inhibition against the fungi in comparison with other plant extracts. This study validates the use of tested medicinal plants in the treatment of various diseases.