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A comparative study on antioxidant activity of water and ethanol extracts of ten Chinese herbs

机译:十种中草药水和乙醇提取物抗氧化活性的比较研究

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摘要

A search of naturally occurring antioxidant compounds from plant sources might provide leads for the development of novel drugs, which may reduce the risk of chronic diseases caused by free radicals. An antioxidant activity and total phenolic content of the water and alcohol extracts of 10 herbs from local pharmacy were studied. The highest phenolic content of the water and alcohol extracts of BSR was found with 36.70 and 91.17 mg PE /g. The flavonoid compounds were found to have the highest content of BSR with 15.58 mg RE for WE.In vitro,the radical-binding activity with DPPH (1,1-dip-henyl-2-picrylhydrazyl radical) and total antioxidant power (Ferric reducing/antioxidant power, FRAP) of ten herbs extracts were determined. At 1.0 mg/ml concentration of herbs, CI and BSR exhibited the good reducing capacity of 0.762 and 0.650. The high correlation values between total phenolic content (TPC) and scavenging efficiency (SE) suggest that the major antioxidant compounds in studied ten herbs might be phenolic compounds.
机译:从植物来源中寻找天然存在的抗氧化剂化合物可能会为开发新药提供线索,这可能会降低由自由基引起的慢性疾病的风险。研究了当地药房的10种草药的水和酒精提取物的抗氧化活性和总酚含量。 BSR水和醇提取物中的最高酚含量为36.70和91.17 mg PE / g。黄酮类化合物在WE中的BSR含量最高,为15.58 mg RE。在体外,与DPPH(1,1-dip-henyl-2-picrylhydrazyl自由基)的自由基结合活性和总抗氧化能力(还原铁确定了十种草药提取物的抗氧化能力(FRAP)。在1.0 mg / ml的草药浓度下,CI和BSR的还原能力分别为0.762和0.650。总酚含量(TPC)和清除效率(SE)之间的高相关性值表明,研究的十种草药中的主要抗氧化剂化合物可能是酚化合物。

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