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Long-Term Follow-Up of Flexible Bronchoscopic Treatment for Bronchial Carcinoids with Curative Intent

机译:柔性支气管镜治疗支气管类癌的长期随访

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Background. Typical pulmonary carcinoids represent less than 5% of primary lung tumors. In patients with typical bronchial carcinoid, formal surgical resection still remains the gold-standard treatment. Data regarding long-term outcome in using flexible bronchoscope-based modalities under conscious sedation is very limited.Objectives. We sought to investigate, over extended follow-up period, the effectiveness of endobronchial resection for carcinoid tumors with curative intent using flexible bronchoscopy.Methods. Nd:YAG laser photoresection using flexible bronchoscope under conscioussedation. Follow-up included repeat bronchoscopy every 6 months and chest CT every year.Results. Ten patients aged 24 to 70 years with endobronchial carcinoid were treated. The tumor location was variable: 2 left Main bronchus, 1 left upper lobe bronchus, 2 right main bronchus, 2 right middle lobe bronchus and 3 right lower lobe bronchus. No major complications were observed. The patients required between 2 and 4 procedures. Patients were followed for a median period of 29 months with no evidence of tumor recurrence.Conclusions. Endobronchial laser photoresection of typical bronchial carcinoids using flexible bronchsocopy under conscious sedation is an effective treatment modality for a subgroup of patients that provides excellent long-term results that are similar to outcome obtained by more invasive procedures.
机译:背景。典型的肺类癌占原发性肺肿瘤的不到5%。对于典型的支气管类癌患者,正规的手术切除仍是金标准治疗。关于在有意识的镇静情况下使用基于支气管镜的灵活方式的长期结果的数据非常有限。我们试图在延长的随访期内研究使用柔性支气管镜对具有治愈目的的类癌进行支气管内切除的有效性。在有意识的情况下使用柔性支气管镜对Nd:YAG激光进行光切除术。随访包括每6个月重复一次支气管镜检查和每年的胸部CT检查。治疗了10例年龄在24至70岁的支气管内类癌患者。肿瘤位置是可变的:2个左主支气管,1个左上支气管,2个右主支气管,2个右中支气管和3个右下支气管。没有观察到重大并发症。患者需要2到4个程序。随访患者的中位时间为29个月,无肿瘤复发的证据。在有意识的镇静作用下使用柔性支气管镜对典型的支气管类癌进行支气管内激光光切除术是一种有效的治疗方式,可用于亚组患者,其长期效果极佳,类似于通过更具侵入性的手术获得的结果。

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