Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion

摘要

Background: abortion is one of the most common complications of pregnancy, occurring in 10­15% of pregnant women, whiles recurrent spontaneous abortion, rate of 2­5%, is defined as 3 spontaneous abortions. Aim of the Work: was to try to find relationship between serum AMH concentration which represent ovarian reserve, Antral Follicular count and any pelvic Structural abnormality using 3D ultrasound in assessment cases with spontaneous recurrent abortion. Patients and Methods: A multicenter, randomized trial included 100 women who were divided into 2 groups; Group 1 , included 50 patients with 3 recurrent abortions and Group 2 , included 50 parous women with regular menstrual cycles and having one or more living child without any history of pregnancy loss or pelvic structural abnormality. Every subject was subjected to assessing hormonal profile including anti-müllerian hormone (AMH) and Transvaginal ultrasonography. Results: AMH was found to have negative correlation with age, number of abortions, FSH and LH. Conclusion: It could be concluded that Anti-Müllerian hormone is the best indicator of ovarian reserve with a high sensitivity and specificity , so ovarian reserve of women with recurrent spontaneous abortions is not defective.