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A descriptive study of health status and health related quality of life in selected outpatients with type 2 diabetes, pathological body mass index and cardiovascular risk in Spain

机译:西班牙2型糖尿病门诊患者的健康状况和健康相关生活质量的描述性研究,病理性体重指数和心血管疾病风险

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Background Ottawa Charter defined health as a resource for everyday life and as an important dimension of health related quality of life (HRqol). Diabetes and obesity have repeatedly been shown as diseases that diminish health status and HRqol. The aim of this study was to measure health status and HRqol in a Spanish sample of obese patients with type 2 diabetes at cardiovascular risk and analyze behavioural, biological and social determinants of health. Methods Outpatients from external specialized clinic in Endocrinology were evaluated. Measurements: sex, age, family history, employment status, comorbidities, pain, lifestyle habits, anthropometrics, blood pressure, blood analysis and HRqol with COOP/WONCA questionnaire (7 dimensions). Statistics: univariate, bivariate, multivariate and comparative analysis. Results Mean age was 59.1?±?7.6 [95%IC: 56.6-61.6], 74% were women and 63.2% were physically active. WONCA values were; summary index (SI): 18.7?±?4 [95%IC: 17.3-20] (maximum 35); physical fitness: 3.3?±?1, feelings: 2.3?±?1.1, social activities: 1.5?±?1, daily activities: 2.1?±?1.2, change in health: 2.7?±?0.9, overall health: 3.6?±?0.7 and pain: 3.5?±?1.2 (maximum 5). High fibrinogen values (339.3?±?85.8 [95%IC: 309.8-368.8]) negatively influenced pain visual analogic scale (p?=?0.029). Physically active patients (63.2%) had better values in daily activities dimension (p?=?0.025). More than the half of the sample (51.5%) reported a good quality of sleep, but the pain worsened it (p?=?0.040). High BMI values (34.8?±?5.8 [95%IC: 32.9-36.7]) harmed the COOP-WONCA SI (p?=?0.009). High glycated hemoglobin (HbA1c) values (6.8?±?1.3 [95%IC: 6.3-7.2]) had a negative impact on COOP-WONCA SI (p?=?0.018). Nor tailored diet (15.8%) or being employed (18.4%) influenced the HRqol. The regression that best models COOP-WONCA SI was adjusted for BMI and HbA1c. SI?=?3.509?+?0.335BMI +0.330HbA1c. Conclusions HRqol was worse than in general population, but better than in previous studies of diabetes patients, without differences by sex or age, though feelings, daily activities and pain dimensions scored worse than in these studies. Higher levels of HbA1c, obesity and procoagulative state had a negative impact in these last dimensions. Pain impaired quality of sleep and physical activity had a positive impact in daily activities. BMI and HbA1c modeled the HRqol.
机译:背景技术《渥太华宪章》将健康定义为日常生活的资源,是健康相关生活质量的重要方面(HRqol)。糖尿病和肥胖已被反复证明是会削弱健康状况和HRqol的疾病。这项研究的目的是测量西班牙2型糖尿病肥胖患者的健康状况和HRqol,分析其心血管风险,并分析健康的行为,生物学和社会决定因素。方法对外部内分泌专科门诊进行评估。使用COOP / WONCA问卷(7个维度)进行测量:性别,年龄,家族史,就业状况,合并症,疼痛,生活方式习惯,人体测量学,血压,血液分析和HRqol。统计数据:单变量,双变量,多元和比较分析。结果平均年龄为59.1±7.6,[95%IC:56.6-61.6],女性74%,体育锻炼63.2%。 WONCA值为;总结指数(SI):18.7±±4 [95%IC:17.3-20](最大35);身体素质:3.3±1,感觉:2.3±1.1,社交活动:1.5±±1,日常活动:2.1±1.2,健康变化:2.7±0.9,整体健康:3.6? ±±0.7,疼痛:3.5±±1.2(最大5)。高纤维蛋白原值(339.3±±85.8 [95%IC:309.8-368.8])对疼痛的视觉类比量表有负面影响(p≥0.029)。体力活动患者(63.2%)的日常活动量值更好(p = 0.025)。超过一半的样本(51.5%)报告了良好的睡眠质量,但疼痛使睡眠恶化(p?=?0.040)。高BMI值(34.8±±5.8 [95%IC:32.9-36.7])损害了COOP-WONCA SI(p≥0.009)。高糖化血红蛋白(HbA1c)值(6.8±±1.3 [95%IC:6.3-7.2])对COOP-WONCA SI有负面影响(p?=?0.018)。量身定制的饮食(15.8%)或受雇的饮食(18.4%)均未影响HRqol。针对BMI和HbA1c调整了最佳模型COOP-WONCA SI的回归。 SI≤3.509≤+ 0.335BMI + 0.330HbA1c。结论HRqol较一般人群差,但比先前的糖尿病患者研究好,且没有性别或年龄的差异,尽管感觉,日常活动和疼痛程度得分较这些研究差。较高水平的HbA1c,肥胖和促凝状态对这些最后方面都有负面影响。疼痛影响睡眠质量和体育锻炼对日常活动产生积极影响。 BMI和HbA1c为HRqol建模。

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