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Study of drug prescription pattern of anti-hypertensives in a tertiary care hospital

机译:三级医院抗高血压药处方模式研究

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To study the antihypertensive drug utilization pattern among Hypertensive patients in a rural tertiary care teaching Hospital at Salem, Tamilnadu, India. A prospective study of 9 month duration was conducted at the tertiary care hospital. The prescriptions containing antihypertensives were collected from the patients attending the outpatient department of general medicine. Pregnant women were excluded from the study. The patient’s demographics, blood pressure, antihypertensive drugs prescribed were entered in a specially designed proforma. A total of 310 prescriptions were monitored, of which 188 were male and 122 were female. The age group of the patients varies from 21 – 70 years. Among 310 hypertensives, 58.38% of patients were treated with dual combinations, 30.64% of patients were treated with single anti-hypertensive drug and 10.96% of patients were treated with triple drug combinations. In monotherapy, angiotensin receptor blocker (Telmisarton) were most commonly prescribed (n=21). In combination therapy, a two drug combination consisting of angiotensin receptor blocker (Telmisarton) and diuretics (hydrochlorthiazide) were given to the majority of patients (n=40; 12.90%). In Triple drug therapy angiotensin receptor blocker (Telmisarton), diuretics (hydrochlorthiazide) and calcium channel blocker (Amlodipine) are the highest prescription (8.06%) for the patients. The study conclude that, ARBs are the most used antihypertensive agent especially Telmisartan. ACEIs are the least prescribed antihypertensive agent. Double and triple combination therapies are more used when compared to monotherepy. In combination therapy ARB and Diuretics (16.23%) are placing the first place in prescription and followed by ARB and CCB (12.73%). The least combination was BB with Diuretics (1.93%)
机译:在印度泰米尔纳德邦塞勒姆市农村三级保健教学医院研究高血压患者的降压药物利用模式。在三级医院进行了为期9个月的前瞻性研究。含有降压药的处方是从就诊于普通科门诊的患者那里收集的。孕妇被排除在研究之外。该患者的人口统计学信息,血压,抗高血压药已按特殊设计的形式输入。总共监测了310张处方,其中男性188张,女性122张。患者的年龄段为21 – 70岁。在310名高血压患者中,有58.38%的患者接受了双重药物治疗,30.64%的患者接受了单一抗高血压药物治疗,10.96%的患者接受了三种药物联合治疗。在单一疗法中,最常开具血管紧张素受体阻滞剂(替米沙顿)(n = 21)。在联合治疗中,大多数患者接受了由血管紧张素受体阻滞剂(Telmisarton)和利尿剂(盐酸氢噻嗪)组成的两种药物组合(n = 40; 12.90%)。在三重药物治疗中,血管紧张素受体阻滞剂(Telmisarton),利尿剂(氢氯噻嗪)和钙通道阻滞剂(氨氯地平)是患者的最高处方(8.06%)。研究得出的结论是,ARBs是最常用的降压药,尤其是替米沙坦。 ACEI是处方最少的降压药。与monotherepy相比,双重和三重联合疗法更为常用。在联合疗法中,ARB和利尿剂(16.23%)在处方中排名第一,其次是ARB和CCB(12.73%)。最少的组合是BB与利尿药(1.93%)

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