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Henoch-Sch?nlein purpura with major gastrointestinal involvement

机译:患有主要胃肠道疾病的过敏性紫癜

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Henoch-Sch?nlein purpura (HSP) is an IgA vasculitisof small vessels manifested by purpura, abdominalpain, articular and renal involvement (1-3). This wasfirst described by Edouard Heinrich Henoch andJohann Lakas Sch?nlein (3). With 20 cases/ 100,000children/ year, the estimated incidence in adults is11.5 times lower than in children (1-3). However, clinicalmanifestations are more ominous in the group ofolder patients (1-3). Worthy of note, the low numberof studies including adults with HSP may hinderthe establishment of protocols about managementguidelines for this patients’ age group (1). The relativelybenign course of HSP in children contrasts with thatamong elderly, and younger patients improve withsteroids, immunosuppressant’s or plasmapheresis (1-3).
机译:过敏性紫癜(HSP)是小血管的IgA血管炎,表现为紫癜,腹痛,关节和肾脏受累(1-3)。这首先由爱德华·海因里希·海诺克(Edouard Heinrich Henoch)和约翰·拉卡斯·施恩莱恩(Johann Lakas Sch?nlein)(3)描述。在20例病例/ 100,000个儿童/年的情况下,成人的估计发病率比儿童(1-3岁)低11.5倍。然而,在老年患者中,临床表现更为不祥(1-3)。值得一提的是,包括HSP成人在内的研究数量很少,可能会阻碍针对该患者年龄组的管理指南方案的建立(1)。儿童中HSP的相对较好的病程与老年人中的HSP相反,而年轻的患者在类固醇,免疫抑制剂或血浆置换方面有所改善(1-3)。

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