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Antimicrobial and physical properties of alginate impression material incorporated with silver nanoparticles

机译:含银纳米颗粒的藻酸盐印模材料的抗菌和物理性能

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Background: Self?disinfecting impression materials would reduce time and energy needed for impression disinfecting process in clinic. The aim of this study was to evaluate the antimicrobial effect of alginate mixed with nanosilver solution at a concentration of 500 ppm and 1000 ppm on common oral microorganisms and assess changes in working time, setting time, and surface detail reproduction. Materials and Methods: In this in vitro study, three groups were assigned. The first group was alginate, the second group was alginate mixed with 500 ppm nanosilver, and the third group was alginate mixed with 1000 ppm nanosilver. Antimicrobial effect on Escherichia coli, Staphylococcus aureus, and Candida albicans was studied using direct contact test in each group (n = 10). Working time (n = 10), setting time (n = 10), and surface detail reproduction (n = 10) were evaluated separately using the ISO 21563 protocol. Descriptive tables were used to describe the data. Kruskal–Wallis test used to determine significant differences in the number of colonies was counted in antimicrobial test (α = 0.05). Results: No adverse effects observed in working time, setting time, and surface detail reproduction of alginate impressions. Alginate mixed with silver nanoparticles showed no inhibitory effect on S. aureus and C. albicans, but the number of E. coli colonies were counted in the group 1000 ppm was significantly lower than 500 ppm (P = 0.001). Conclusion: Antimicrobial effect of alginate mixed with silver nanoparticles is not clinically indicated. Nevertheless, its physical features did not change significantly.
机译:背景:自我消毒的印模材料将减少临床中印模消毒过程所需的时间和能量。这项研究的目的是评估以500 ppm和1000 ppm浓度混合的藻酸盐与纳米银溶液对常见口腔微生物的抗菌作用,并评估工作时间,凝固时间和表面细节复制的变化。材料和方法:在这项体外研究中,分为三组。第一组为藻酸盐,第二组为藻酸盐与500 ppm纳米银的混合物,第三组为藻酸盐与1000 ppm纳米银的混合物。使用直接接触试验对每组(n = 10)研究了对大肠杆菌,金黄色葡萄球菌和白色念珠菌的抗菌作用。使用ISO 21563协议分别评估工作时间(n = 10),设置时间(n = 10)和表面细节再现(n = 10)。描述性表用于描述数据。用于确定菌落数量显着差异的Kruskal–Wallis试验在抗菌试验中计数(α= 0.05)。结果:在工作时间,凝固时间和藻酸盐压痕的表面细节再现方面均未观察到不利影响。海藻酸盐与银纳米颗粒的混合对金黄色葡萄球菌和白色念珠菌没有抑制作用,但是在1000 ppm组中计数的大肠杆菌菌落数明显低于500 ppm(P = 0.001)。结论:海藻酸盐与银纳米颗粒混合的抗菌作用未在临床上表明。然而,其物理特征并没有明显改变。

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