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Review- Methodologies for the study of polyphenolic compounds in forage species: A historic review

机译:综述-饲草物种中多酚化合物的研究方法:历史回顾

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By means of the representative scientific publications review on the tannins biochemistry, the main results related to their beneficial and antinutritional properties from chemistry-analytical, in vitro and in vivo studies were presented. The paragraphs are greater relevance and the repercussion of the knowledge acquired on these compounds is described; in the development of viable strategies of feeding. Historically, until the chemistry of natural products was not developed quantitatively, the animal nutrition studies with phenolic forages sources were insufficient. The first tests made after 1950, were directed to the phytochemical characterization of the majority tannin sources and the determination of the biological activity of the main groups, with particular emphasis in fodder leguminous like additional resource of nutrients. In one second stage the analytical techniques were implemented and validated that would be used to describe the polyphenols antifeeding effect and its interaction with the primary and secondary metabolites. The critic concentrations, in which these compounds could affect the good digestive process of ruminants and monogastric were postulated. Besides, the detrimental action of tannins hydrolysables and condensed in different conditions of feeding was compared, determining the variables of greater influence in the toxicological action. Independently to that the investigations made until the present have contributed much information as far as the characteristics of vegetal tannins, at the present time exists important subjects such as, the mechanisms related to the antihelmintic effect, the ecological function of hydrolysables tannins in non leguminous species and the interaction of polyphenols with alkaloids; among others, that have not been boarded with force; reason why integral studies need to explain these urgent questions.
机译:通过对单宁生物化学的代表性科学出版物的综述,提出了与化学,分析,体外和体内研究有关的有益和抗营养性质的主要结果。这些段落具有更大的相关性,并描述了对这些化合物获得的知识的回响;在制定可行的喂养策略中。从历史上看,直到天然产物的化学尚未得到定量发展,用酚醛饲草来源的动物营养研究还是不够的。 1950年后进行的首批测试针对大多数单宁来源的植物化学特征以及主要组份的生物活性的测定,尤其侧重于豆科饲料,如其他养分资源。在第二阶段,实施并验证了分析技术,该技术将用于描述多酚的反喂作用及其与主要和次要代谢物的相互作用。推测了这些化合物可能影响反刍动物和单胃动物良好消化过程的浓度。此外,比较了单宁在不同的进料条件下可水解物和冷凝物的有害作用,确定了对毒理作用影响更大的变量。到目前为止,就植物单宁的特性而言,独立进行的研究已经提供了很多信息,目前,存在重要的课题,例如与抗蠕虫作用的机制,非豆科物种中可水解单宁的生态功能有关。多酚与生物碱的相互作用;除其他外,还没有被强行登上;整体研究需要解释这些紧急问题的原因。

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