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Identification of diagnostic markers involved in the pathogenesis of gastric cancer through iTRAQ-based quantitative proteomics

机译:通过基于iTRAQ的定量蛋白质组学鉴定与胃癌发病机制有关的诊断标记

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We provide detailed datasets from our analysis of proteins that are differentially expressed in gastric cancer tissues compared with adjacent normal gastric tissues, as identified by iTRAQ-based quantitative proteomics. Also included is a set of representative images of immunohistochemical staining of gastric cancer tissues showing four levels of expression of fatty acid binding protein (FABP1) and fatty acid synthase (FASN). The data presented in this paper support the research article “Quantitative proteomic analysis reveals that proteins required for fatty acid metabolism may serve as diagnostic markers for gastric cancer”?(Jiang et al., 2017) [1]. We expect that the data will contribute to the identification of sensitive and specific biomarkers for early detection of gastric cancer.
机译:通过基于iTRAQ的定量蛋白质组学鉴定,我们从胃癌组织中与相邻正常胃组织相比差异表达的蛋白质分析中提供了详细的数据集。还包括一组胃癌组织免疫组织化学染色的代表性图像,显示了四个水平的脂肪酸结合蛋白(FABP1)和脂肪酸合酶(FASN)表达。本文提供的数据支持研究文章“定量蛋白质组学分析揭示了脂肪酸代谢所需的蛋白质可能是胃癌的诊断标志物”(Jiang等人,2017)[1]。我们希望这些数据将有助于识别早期胃癌的敏感和特异性生物标志物。

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