Adrenal oncocytic pheochromocytoma with functionality in a neurofibromatosis patient: A case report

摘要

BackgroundThere are 4 prior reports of oncocytic pheochromocytoma of the adrenal. It may histologically resemble cortical carcinoma, which also can have oncocytic cells.Case presentationWe report a 54-year-old male with neurofibromatosis 1 who had an endocrinologically functional, 13.5?cm tumor. Histology showed mostly oncocytic cells. An adrenalectomy showed that the tumor had capsular and vascular invasion. Symptoms were cured by surgery. A cortical carcinoma with oncocytic change was initially favored, but the clinical history together with immunostain results were consistent with pheochromocytoma with oncocytic change.ConclusionsIn conclusion, the clinical history was crucial to the diagnosis. This is the first tumor of this type in a neurofibromatosis patient and the first in which functional effects were caused.