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A dural metastatic small cell carcinoma of the gallbladder as the first manifestation: a case report

机译:胆囊硬膜转移性小细胞癌的首发表现:一例报告

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A dural metastasis is one of the essential differential diagnoses of meningioma. In general, carcinomas of the breast and lung in females and prostate in males have been the most commonly reported primary lesions of dural metastases. However, dural metastasis of gallbladder carcinoma is extremely rare. Here, we report a unique case of a dural matter metastasis of gallbladder carcinoma as the first manifestation, which was autopsy-defined as small cell carcinoma. A 78-year-old man came to our hospital complaining of left hemianopia. Brain computed tomography (CT) revealed a sizeable parasagittal dural-based extra-axial tumor. However, the findings for meningioma were atypical by magnetic resonance imaging, suggesting a meningioma mimic. A contrast-enhanced CT scan of the abdomen revealed a large gallbladder carcinoma. The patient opted for the best supportive care and died 2?months later. The post-mortem examination revealed small cell carcinoma in gallbladder carcinoma. Moreover, an immunologically similar carcinoma was detected in the dural metastasis. To the best of our knowledge, this is the first case of a dural metastasis of gallbladder small cell carcinoma. A systemic examination is essential for clinicians when atypical findings of meningioma are observed, suggesting a meningioma mimic. We present this rare case with a review of the literature.
机译:硬脑膜转移是脑膜瘤的重要鉴别诊断之一。通常,女性最常报告的硬脑膜转移灶是女性的乳腺癌和肺癌,男性的前列腺癌。但是,胆囊癌的硬脑膜转移极为罕见。在这里,我们报告胆囊癌的硬脑膜转移的独特情况为第一个表现,这是尸检定义为小细胞癌。一名78岁的男子因左偏盲来到我们医院。脑计算机断层扫描(CT)显示较大的基于矢状旁硬脑膜的轴外肿瘤。然而,通过磁共振成像发现脑膜瘤的发现是非典型的,提示存在脑膜瘤的模仿。腹部CT增强扫描显示胆囊癌大。该患者选择了最佳的支持治疗,并在2个月后死亡。尸检显示胆囊癌中有小细胞癌。此外,在硬脑膜转移中检测到免疫学相似的癌。据我们所知,这是胆囊小细胞癌硬脑膜转移的第一例。当观察到非典型性脑膜瘤发现时,全身检查对于临床医生来说是必不可少的,这提示了脑膜瘤的模仿。我们通过文献综述介绍这种罕见的情况。

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