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A dural metastatic small cell carcinoma of the gallbladder as the first manifestation: a case report

机译:胆囊的多云转移性小细胞癌作为第一个表现形式:案例报告

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Abstract Background A dural metastasis is one of the essential differential diagnoses of meningioma. In general, carcinomas of the breast and lung in females and prostate in males have been the most commonly reported primary lesions of dural metastases. However, dural metastasis of gallbladder carcinoma is extremely rare. Here, we report a unique case of a dural matter metastasis of gallbladder carcinoma as the first manifestation, which was autopsy-defined as small cell carcinoma. Case presentation A 78-year-old man came to our hospital complaining of left hemianopia. Brain computed tomography (CT) revealed a sizeable parasagittal dural-based extra-axial tumor. However, the findings for meningioma were atypical by magnetic resonance imaging, suggesting a meningioma mimic. A contrast-enhanced CT scan of the abdomen revealed a large gallbladder carcinoma. The patient opted for the best supportive care and died 2 months later. The post-mortem examination revealed small cell carcinoma in gallbladder carcinoma. Moreover, an immunologically similar carcinoma was detected in the dural metastasis. Conclusions To the best of our knowledge, this is the first case of a dural metastasis of gallbladder small cell carcinoma. A systemic examination is essential for clinicians when atypical findings of meningioma are observed, suggesting a meningioma mimic. We present this rare case with a review of the literature.
机译:摘要背景多云转移是脑膜瘤的基本鉴别诊断之一。通常,女性乳腺癌和肺部的癌症和雄性前列腺癌是最常见的多云转移的主要病变。然而,胆囊癌的硬膜膜转移极为罕见。在这里,我们报告了胆囊癌作为第一种表现形式的独特物质转移的案例,其是尸检定义为小细胞癌。案例演讲是一名78岁的男子来到我们院长的抱怨左上半血病。脑计算断层扫描(CT)揭示了一种大量的促剖腹腺盆型超轴向肿瘤。然而,通过磁共振成像,脑膜瘤的发现是非典型的,表明脑膜瘤模仿。腹部的对比增强CT扫描显示出大的胆囊癌。患者选择最好的支持性护理,并在2个月后死亡。后验尸检查显示胆囊癌中的小细胞癌。此外,在多核转移中检测到免疫接种相似的癌。尽管我们所知的结论,这是胆囊小细胞癌多云转移的第一种情况。当观察到脑膜瘤的非典型发现时,全身检查对于临床医生至关重要,表明脑膜瘤模仿。我们在审查文献中提出了这一罕见的案例。

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