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The Study of Egg Allergy in Children With Atopic Dermatitis

机译:儿童特应性皮炎鸡蛋过敏的研究

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Context Food allergy plays a significant pathogenic role among children with atopic dermatitis (AD). Objective The aims of this study were to evaluate allergy to egg in these children and determine the egg specific immunoglobulin E (IgE) cutoff point. Design and Setting It was a cross-sectional study that took place at Immunology, Asthma and Allergy Research Institute from 2005 to 2007. Methods Children younger than 14 years old with AD entered the study. Careful medical histories were taken and skin prick and Immuno-CAP tests with the most commonly offending foods (cow's milk, egg, wheat, peanut, and soy) were performed. Children with a clear, positive history of food allergy and a positive IgE-mediated test or those with positive responses to both IgE-mediated tests were determined to have food allergies. The egg-specific IgE level cutoff point was determined. Results A hundred patients entered the study (from 2 months to 12 years old). They were divided into 3 age groups: first Conclusion Prevalence of egg allergy is highly significant in patients with AD.To use egg-specific IgE level cutoff point, the patient population under study must be considered.
机译:背景食物过敏在特应性皮炎(AD)患儿中起着重要的致病作用。目的这项研究的目的是评估这些儿童对卵的过敏反应,并确定卵特异性免疫球蛋白E(IgE)的临界点。设计与设置这是一项横断面研究,于2005年至2007年在免疫学,哮喘和过敏研究所进行。方法研究对象为14岁以下患有AD的儿童。仔细检查病史,并用最常见的食物(牛牛奶,鸡蛋,小麦,花生和大豆)进行皮肤点刺和Immuno-CAP测试。确定食物过敏史明确,IgE介导测试阳性或对两种IgE介导测试阳性的儿童具有食物过敏。确定了卵特异性IgE水平的临界点。结果100名患者进入研究(2个月至12岁)。他们分为3个年龄组:第一个结论AD患者的鸡蛋过敏患病率非常高。要使用鸡蛋特异的IgE水平截止点,必须考虑所研究的患者人群。

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