Hemolytic anemia caused by Ditaxis desertorum (Euphorbiaceae) in cattle

摘要

.- Tokarnia C.H., Chagas B.R., Chagas A.D. & Silva H.K. 1997. [Hemolytic anemia caused by Ditaxis desertorum (Euphorbiaceae) in cattle.] Anemia hemol?-tica causada por Ditaxis desertorum (Euphorbiaceae) em bovinos. Pesquisa Veterin??ria Brasileira 17(3/4):112-116. Projeto Sa?ode Animal-Embrapa/UFRRJ, Km 47, Serop??dica, RJ 23851-970, Brazil. Ditaxis desertorum Pax et K. Hoffm., a herbaceous plant of the Euphorbiaceae family, caused hemoglobinuria due to its hemolytic properties, when force-fed fresh to bovines in daily doses of 1.0 to 2.5 g/kg; the hemoglobinuria appeared from the 4th to 8th day of the experiment. After a period of 3 to 5 days of severe hemoglobinuria and anemia, these symptoms disappeared in three of the four animals, although they continued to receive the plant. There was a rapid return to normal blood composition after cessation of the hemoglobinuria. The fourth bovine, which received 2.5 g/kg/day, over 5 days, had severe hemoglobinuria and anemia during the last 4 days of life and died on the 8th day. Post-mortem and histopathological examinations revealed hemoglobinuric nephrosis and liver distrophy with centrolobular necrosis of the parenchyma. A single dose of 7.7 g/kg or doses of 2.5 and 3 g/kg/day given during 2 days, caused colics and death within a few hours in the three other bovines; post-mortem examinations revealed congestion and oedema of the wall of rumen and reticulum. Case histories indicate that under natural conditions of ingestion only the hemolytic anemia occurs. Although palatable, the ingestion of D. desertorum in sufficient amounts to cause colics and lesions of the forestomachs is probably limited by its caustic properties. INDEX