Hemolytic Anemias: Membrane Defects.

摘要

An approach to understanding the properties of the red cell membrane involves consideration of each of its components: protein, lipid, carbohydrate, and the combinations of these. Such molecular species are not static during the life span of the red cell but undergo dynamic change with membrane synthesis, accretion, loss, and destruction. This chapter presents some fundamental concepts of the normal erythrocyte membrane and then deals with the pathogenesis of disorders leading to membrane failure and hemolysis. Keywords: Red blood cells; Cells; Biology; Cell membranes; Reprints. (KT)