A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that includedfatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs. A solitary,brown-red-coloured mass, approximately 0.5 cm thick and 1.5 × 2 cm in diameter, was detected on the right sideof the medulla oblongata, pons and cerebellum. The cut surface showed no invasion of the brain parenchyma.Histologically, the neoplasm was characterised by proliferation of endothelial cells, which showed epithelioidand spindle cell features. Some tumour cells had intracytoplasmic lumen formations containing red blood cells.The nuclei of the tumour cells were large and vesicular. In immunohistochemical experiments the tumour cellsstained positive for factor VIII-related antigen, CD31 and CD34. A description is provided of the features ofthis epithelioid and spindle-cell haemangioendothelioma (EHE) that originated from vessels of the meninges inthe subarachnoid space.
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