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Teriparatide and vertebral fracture healing in Ankylosing Spondylitis

机译:强直性脊柱炎的特立帕肽和椎骨骨折愈合

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Summary Patients with Ankylosing Spondylitis (AS) are four times more likely to sustain spinal fractures. Due to the associated risk of neurological complications treatment is complex. We present the case of a 56-year-old Caucasian gentleman with AS who sustained a fracture of T2 vertebra following a traumatic hyperextension injury. He declined surgery in fear of complications and started treatment with subcutaneous Teriparatide at a dose of 20mg daily for six months. There was complete healing of the vertebral fracture at 6months without any complications. This case is unique as complete healing was achieved without preceding surgical intervention. Further exploration of the use of Teriparatide in spinal fractures in patients with AS is recommended to support the theories generated by this and other existing cases in the literature.
机译:小结强直性脊柱炎(AS)患脊柱骨折的可能性是四倍。由于存在神经系统并发症的相关风险,因此治疗非常复杂。我们介绍了一个56岁的高加索绅士绅士的案例,该人在外伤性过度伸展损伤后遭受T2椎骨骨折。由于担心并发症,他拒绝手术,并开始使用每日20mg剂量的皮下注射特立帕肽治疗六个月。 6个月时椎骨骨折完全愈合,没有任何并发​​症。这种情况是独特的,因为无需事先进行外科手术即可完全治愈。建议进一步探讨特立帕肽在AS患者脊柱骨折中的应用,以支持这种情况以及文献中其他现有案例所产生的理论。

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