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首页> 外文期刊>Turkish Journal of Electrical Engineering and Computer Sciences >Investigating the occurrence mechanism of cytokine-like formations by the electromagnetic approach
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Investigating the occurrence mechanism of cytokine-like formations by the electromagnetic approach

机译:用电磁学方法研究细胞因子样形成的发生机理

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摘要

This study aims to elucidate the production mechanism of cytokine-like formations secreted from T cells and similar cells by electromagnetic modeling techniques. Three Hertz dipole antennas polarized in arbitrary directions were placed without touching each other at the center of spherical T-cell models to test the Canbay hypothesis about the formation mechanism of cytokines (CHAFMOC) on T-cell surfaces. A dielectrophoretic force field was created within the gelatin layer of the T-cell model. The prepared control and electromagnetically stimulated T-cell model samples were incubated in water in a glass container in a Faraday cage for the specified period and then photographed. At the end of the experiments, cytokine-like formations were observed in the samples, depending on their contents. The results of these experiments, carried out in accordance with the CHAFMOC, show that a dielectrophoretic force is the main cause of the cytokine formation and secretion mechanism in the outer layers of rough T-cell models. Given these results, new approaches and developments may be expected to better our understanding of the immune system in the subjects of cell science, pharmacology, and bioengineering.
机译:本研究旨在通过电磁建模技术阐明从T细胞和类似细胞分泌的细胞因子样形成的产生机理。将三个在任意方向极化的赫兹偶极子天线放置在球形T细胞模型的中心而彼此不接触,以测试有关T细胞表面细胞因子(CHAFMOC)形成机理的Canbay假设。在T细胞模型的明胶层内产生了介电泳力场。在法拉第笼中的玻璃容器中的水中将制备的对照和电磁刺激T细胞模型样品孵育指定时间,然后拍照。在实验结束时,根据其含量,在样品中观察到了类似细胞因子的形成。根据CHAFMOC进行的这些实验的结果表明,介电泳力是粗糙T细胞模型外层中细胞因子形成和分泌机制的主要原因。鉴于这些结果,新方法和新进展有望使我们更好地理解细胞科学,药理学和生物工程学领域的免疫系统。

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