Antioxidant potential and secondary reactivity of bis${$diphenyl(2-pyridyl)phosphino$}$copper(II) complex

摘要

Copper-based complexes with the general formulas [Cu(L)$_{2}$]Cl$_{2}$ (1 ) and [Cu$_{2}$L$_{2}$($mu_{2}$-L)$mu_{2-}$Cl$_{2}$] (2 ) and a mixed-ligand anionic complex [Cu(L)$_{2}$dedtc][LCl] (3b ), where L = diphenyl(2-pyridyl)phosphine and dedtc = diethyldithiocarbamate, were synthesized and structurally characterized. X-ray analysis revealed that the coordination environment around the copper atom in complexes 1-3 is distorted tetrahedral. In monomeric complexes 1 and 3b both diphenyl(2-pyridyl) phosphine ligands are monodentate and are coordinated through the P-atom. In complex 3b two phosphine ligands are attached to copper through the P-atom. The third phosphine ligand acts as a bridged ligand, coordinated to the metal centers through the P-atom and N-atom. Complexes 1 and 3b were tested for radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH) as a free radical. A prominent color change after mixing the solution of complex 1 and DPPH was observed, indicating the efficiency of the compound as antioxidant.