A Case of Superwarfarin Poisoning Due to Repetitive Occupational Dermal Rodenticide Exposure in a Worker

摘要

Superwarfarin poisoning is usually due to chronic occult small-doseexposures and can easily be misdiagnosed and may lead to seriouscomplications. The diagnosis can be confirmed by a concordanthistory and analyses of blood and urine specimens with the liquidchromatography with tandem mass spectrometry (LC-MS/MS)technique. Several months of continuous treatment with high dosesof daily oral vitamin K, as well as other supportive measures, arewarranted, especially when repeated laboratory measurements to helppredict the treatment period are not available. In this paper, a caseof superwarfarin poisoning due to chronic repetitive occupationaldermal exposure to commercial rodenticides is presented.