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首页> 外文期刊>Turkish Journal of Hematology >Cerebral Sinovenous Thrombosis Mimicking Intracranial Mass
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Cerebral Sinovenous Thrombosis Mimicking Intracranial Mass

机译:模仿颅内肿块的脑静脉血栓形成

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摘要

Cerebral sinovenous thrombosis is rare in children [1]. Mostcommon signs and symptoms are seizure, lethargy, and headache[1,2,3]. We herein report a case diagnosed as cerebral sinovenousthrombosis mimicking an intracranial mass and presenting withincreased intracranial pressure symptoms in an adolescent girl.A 16-year-old girl was admitted to our emergency service withcomplaints of headache, vomiting, and confusion. Her pastmedical history was unremarkable. Physical examination revealedfacial paralysis and motor weakness on the left side. Magneticresonance (MR) imaging disclosed a mass (65x42x55 mm) in theright temporal lobe shifting the midline structure from rightto left (Figure 1). Because of herniation findings, surgery wasperformed immediately. Histopathologic investigation showed thrombosis associated with iron deficiency, two cases with normal platelet count have also been described [7]. As not all cases of iron-related thrombotic events occur in patients with concomitant high platelet counts, other pathogenic mechanisms have been proposed. One of these explanations is that iron deficiency may contribute to a hypercoagulable state by affecting blood flow patterns within the vessels because of reduced deformability and increased viscosity of microcytic red blood cells. Furthermore, anemic hypoxia secondary to iron deficiency has been suggested to precipitate situations of increased metabolic stress, in particularly in vulnerable areas of the brain supplied by end arteries [8]. In our patient, iron deficiency may also have contributed to the development of thrombosis.
机译:儿童脑静脉血栓形成罕见[1]。最常见的体征和症状是癫痫发作,嗜睡和头痛[1,2,3]。我们在此报告一例诊断为脑窦静脉血栓形成的病例,该病例模仿一名少女的颅内肿块,并表现出颅内压增高的症状。一名16岁女孩因头痛,呕吐和神志不清被送往我们的急诊室。她的医史不多。体格检查显示左侧面瘫和运动无力。磁共振(MR)成像显示右侧颞叶有一个肿块(65x42x55 mm),使中线结构从右向左移动(图1)。由于发现了疝,因此立即进行了手术。组织病理学检查显示血栓形成与铁缺乏症有关,也有2例血小板计数正常的病例[7]。由于并非所有与铁有关的血栓形成事件都发生在伴有高血小板计数的患者中,因此提出了其他致病机制。这些解释之一是铁缺乏症可能通过影响血管内的血流模式而导致高凝状态,这是由于变形能力降低和微细胞红细胞粘度增加所致。此外,已建议继发于铁缺乏症的贫血性缺氧会加剧代谢压力的增加,特别是在末梢动脉供应的大脑脆弱区域[8]。在我们的患者中,铁缺乏症也可能导致血栓形成。

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