ESTIMATION OF TOTAL PHENOLIC AND FLAVONOIDS CONTENT AND ANTI-FREE RADICAL SCAVENGER, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF EXTRACT OF Matricaria pubescens (DESF.) SCH. BIP. COLLECTED FROM SOUTH EAST OF ALGERIA

摘要

The aim of this study for evaluated of extract of aerial parts of an endemic Saharan African plant Matricaria pubescens (Desf.) Sch. Bip. was examined for radical scavenging capacities and antimicrobials activity. The total of phenolic compounds of the extract was found to be 103.5 mg/g of dry extract. The antioxidant activity determined by the DPPH? method revealed that the extract had the highest antioxidant activity on DPPH? free radicals (97.1%). A significant correlation was observed between total polyphenols and the antioxidant activity. The total antioxidant capacity the inhibition effects of Matricaria pubescens extract on linoleic acid emulsion peroxidation were found to be 94.17% at 2 mg/ml. Also, the strongest antibacterial effect of the extract was recorded against Bacillus subtilus and Candida albicans whereas a mild inhibition was observed against Escherichia coli, Staphylococcus aureus and Penicillium expansum.