The Effects of Pulsed Electromagnetic Field Treatment in Pain Due to Diabetic Polyneuropathy

摘要

Objectives: Diabetic polyneuropathy is the most common and disabled complication of diabetes mellitus. Pharmacological treatment of diabetic neuropathy is limited because of the side efects of the drugs, used in the treatment of diabetic neuropthy. Alternative treatments are also used in diabetic neuropathy. Systemic side effects of non-pharmacological treatment modalities are rare. We evaluated the value of pulsed electromagnetic field treatment in patients with pain due to diabetic polyneuropathy. Patients and Methods: Symptomatic 95 patients were included in the study, and from these patients, 25 patients were randomized in pulsed electromagnetic field treatment group and 25 patients were randomized in placebo group. Pulsed electromagnetic field device was applied over both feet of the patients for one hour a day (during 10 days). Visual analog scale and neuropathic pain scale of all patients were performed before and after treatment and 6th week. Electroneuromyography was also performed before treatment and 6th week. Results: Improvement of pain determined by visual analog scale was 53% after treatment and 67% six weeks later. The improvement of visual analog scale scores were statistically significant in study group when compared with control subjects. Conclusion: The pulsed electromagnetic field may be an alternative treatment modality in diabetic patients with neuropathic pain. Ama?: Diyabetik periferik n?ropati, diyabetin en s?k g?rülen ve ?zürlülü?e neden olan komplikasyonudur. N?ropatik a?r? s?kl?kla ?oklu farmakolojik tedaviye diren?lidir ve bu ajanlar?n yan etkileri kullan?mlar?n? s?n?rlar. N?ropatik a?r? tedavisinde farkl? alternatif tedaviler ara?t?r?lmaktad?r. Nonfarmakolojik tedavilerin sistemik yan etkileri dü?üktür. Bu rasgele se?ilmi?, plasebo kontrollü ?al??mada, diren?li diyabetik n?ropatik a?r?da puls elektromanyetik alan tedavisinin etkinli?i ara?t?r?ld?. Hastalar ve Y?ntemler: ?al??ma, rasgele ayr?lan, 25 puls elektromanyetik alan tedavisi (PEMF) ve 25 plasebo grubunda olmak üzere 50 hastayla tamamland?. Tedavi grubundaki hastalar?n her iki aya??na on ard???k gün ve günde 1 saat PEMF uyguland?. Olgular?n tedaviden ?nce, sonra ve 6. haftadaki kontrollerinde vizüel analog skala ve n?ropatik a?r? skala de?erlendirmeleri yap?ld?. Elektron?romiyografi tetkikleri, tedaviden ?nce ve 6. hafta kontrollerinde de?erlendirildi. Bulgular: ?al??man?n sonucunda, vizüel analog skala ile yap?lan a?r? de?erlendirmesinde tedavi sonunda %53, kontrol de?erlendirmesinde %67 iyile?me saptand?. N?ropatik a?r? skalas? farkl? verilerinde saptanan düzelme, tedavi grubunda plasebo grubuna g?re istatistiksel olarak anlaml?yd?. Sinir ileti h?z? ?al??malar?nda iki grup verileri aras?nda anlaml? istatistiksel fark saptanmad?. Sonu?: Puls elektromanyetik alan tedavisi, a?r? skorlar? ve polin?ropati semptomlar? üzerindeki olumlu etkileri ile diyabetik n?ropatik a?r? tedavisinde alternatif bir se?enek olarak dü?ünülebilir.