Compounds derived from N - prop - 2 - inil carboxamide, Transient Receptor Potential antagonists of the subfamily, member 1 (TRPA1); Pharmaceutical composition that comprises, and Method for the treatment of neuropathic pain, pain in diabetic polyneuropathy, postoperative pain and pain For Cancer, among others.

摘要

Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.