A POSSIBLE TREATMENT OF ENDEMIC GOITER IN YOUNG UNMARRIED FEMALES.

摘要

Background: The Significant role of iodine as a remedy for endemic goiter iswell known. But Major problem is iodine loss due to sublimation. Ananas Comosus may bea good source of iodine. Study Design: Randomized controlled study. Setting: Departmentof Physiology, PGMI, Lahore in collaboration with DHQ teaching hospital D.G. Khan. Period:May to August 2017. Materials and Methods: Study objective was to measure efficacy ofFresh Ananas Comosus among young unmarried female with endemic goiter. Simple randomsampling technique was applied. Seventy newly diagnosed cases of endemic goiter wereselected by simple random sampling. 35 subjects were included in study group and 35subjects were taken as control group. Dose of Ananas Comosus was standardized by P.C.S.I.Rlaboratories complex Lahore. Data Analysis was carried out by using SPSS version 16.0. Forcomparison of different groups, t-test was used Results: The baseline goiter size (mean + SD)of study group (n=29) and control group (n=30) was non-significantly different. After 8 weeks ofintervention goiter size was highly significantly (P0.001) reduced in study group. Mean serumTSH suppression was also significant. Serum T4 and T3 levels also showed improvement after8 weeks of Ananas Comosus ingestion. Conclusion: Fresh Ananas Comosus can be used astherapeutic agent for endemic goiter patients.