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The Antioxidant Phytochemicals of Nutraceutical Importance

机译:营养重要性的抗氧化植物化学物质

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Over production of free radicals result in oxidative stress that deregulates the cellular and metabolic functions.Phytochemicals with antioxidant property are of great interest due to their beneficial effects on human health as they offerprotection against metabolic dysfunction, gastro-duodenal pathogenesis, premature aging, inflammation, rheumatoid arthritis,atherosclerosis, cancer, neuro-degenerative and cardiovascular diseases. Carotenoids, tocopherols, ascorbates,lipoic acids, polyphenols and enzymes like super oxide dismutase, catalase, glutathione peroxidase, glutathione reductaseare strong natural antioxidants with free radical scavenging activity. Fruits, vegetables, cereals, legumes and beverages arethe main sources of polyphenols. Flavonoids possess ideal structural characteristics, which are responsible for their pharmacologicalproperties and are also powerful metal chelators. The future of dietary antioxidants hold a great promise toensure a better disease free lifestyle for the mankind by scavenging free radicals and consequently preventing mutagenicchanges and associated disorders.
机译:自由基的过度产生导致氧化应激使细胞和代谢功能失控。具有抗氧化特性的植物化学物质对人体健康具有有益的作用,因为它们提供了抵抗代谢异常,十二指肠发病机制,过早衰老,发炎,类风湿关节炎,动脉粥样硬化,癌症,神经退行性疾病和心血管疾病。类胡萝卜素,生育酚,抗坏血酸,硫辛酸,多酚和酶(如超氧化物歧化酶,过氧化氢酶,谷胱甘肽过氧化物酶,谷胱甘肽还原酶)是具有自由基清除活性的强天然抗氧化剂。水果,蔬菜,谷物,豆类和饮料是多酚的主要来源。类黄酮具有理想的结构特征,这是其药理特性的原因,也是强力的金属螯合剂。饮食抗氧化剂的未来有望通过清除自由基从而防止诱变和相关疾病来确保人类更好的无病生活方式。

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