Food Allergy in Children with Asthma: Prevalence and Correlation with Clinical Severity of Respiratory Disease

摘要

Epidemiological evidence suggests that there is a link between asthma and food allergy. The aim of this studywas to estimate the prevalence of food allergy in asthmatic children and to evaluate a possible impact of food allergy onasthma severity. The study enrolled 103 asthmatic children (mean age: 11 years). Skin prick-test, dosage of specific IgE toa standardized panel of inhalant and food allergens and spirometric evaluation was made for each patient. Twenty-four(23%) patients presented food allergy, 75 (77%) were sensitized to at least one food. A lower rate of children with controlledsymptoms was found in children with food allergy and a higher rate of persistent asthma was found in childrensensitized to at least 4 foods. In conclusion, food allergy/sensitization should always be investigated in asthmatic childrenfor its association with increasing severity (only in food sensitized patients) and reduced control of asthmatic symptoms.