Testicular metastasis from renal cell carcinoma is very rare with 15 cases being identified in the literature. A 61-year old white male was admitted to our clinic with a past history of left kidney nephrectomy for renal cancer in 1993 elsewhere. In 1994 a CT-scan showed adrenal metastasis which had been resected. In 1997 2 lung metastases had been detected. The patient was referred to the oncological department. He responded very well to immunotherapy with interferon gamma, GM-CSF and interleukin and is still in stable disease of lung metastases. He now presents with a suspected carcinoma of the left testis. After left inguinal orchiectomy the histological findings showed metastasis from a clear-cell carcinoma. Late intrascrotal metastasis is a rare event in the course of the disease. Introduction Testicular metastasis from renal cell carcinoma is very rare with 15 cases being identified in the literature [1] and accounts for approximately 0.9% of all testicular neoplasms.[2] 153 cases of testicular metastases have been reported so far in a large literature analysis[1], with the common primary sources originating from the prostate, lung and the gastrointestinal tract.Approximately one third of patients with renal carcinoma have haematogenous metastases at the time of diagnosis and an additional 25% of patients develop metastases sometime after having a nephrectomy. The common sites for distant metastatic disease are the lung (50%), bones (30%), liver (30%) brain and thyroid (25%).[3] Case Report A 61-year old white male was admitted to our clinic in August 1999 with a suspected carcinoma of the left testis. Physical examination revealed normal external genitals with the exception of swelling and induration of the left testis. Ultrasound examination resulted in high suspicion for testicular tumor. Therefore, left inguinal orchiectomy was carried out. The histological findings demonstrated metastasis from a clear cell carcinoma.
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