References(21) Neonatal Japanese Black (JB) calves show a high incidence of diarrhea. The objective of this study was to analyze the immune cell populations of neonatal JB calves in detail and examine its correlation with the incidence of diarrhea immediately after birth. Understanding the immune cell populations is helpful in clinics in order to determine the condition of the immune system for prevention of diseases. Blood samples were obtained from JB calves on the day of birth. The peripheral leukocyte populations were analyzed separately for calves that had diarrhea within 2 weeks after birth (diarrhea group; n=26) and for calves without diarrhea (control group; n=74). The numbers of the peripheral blood CD3+TcR1-N12+ and CD8+ T cells were significantly lower in the diarrhea group compared with the control group. These findings suggest that the congenital lower peripheral γδ and CD8+ T cells results in a high risk of diarrhea in neonatal JB calves.
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机译：参考文献（21）新生儿日本黑小牛（JB）腹泻的发生率很高。这项研究的目的是详细分析新生儿JB犊牛的免疫细胞群，并检查其与出生后腹泻发生率的相关性。了解免疫细胞的数量在临床上有助于确定免疫系统的状况以预防疾病。在出生当天从JB小牛获得血液样本。分别分析出生后两周内有腹泻的小牛（腹泻组; n = 26）和无腹泻的小牛（对照组; n = 74）的外周白细胞群。腹泻组外周血CD3 + TcR1-N12 +和CD8 + T细胞的数量明显低于对照组。这些发现表明，先天性外周γδ和CD8 + T细胞降低导致新生儿JB小牛腹泻的高风险。
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