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Brand Name Statin Prescribing in a Resident Ambulatory Practice: Implications for Teaching Cost-Conscious Medicine

机译:在居民门诊实践中使用他汀类药物处方:对讲究成本的医学的启示

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What was known There are calls to enhance residents' awareness of the cost implications of their therapeutic decisions.;What is new A study assessed factors at the resident and encounter level that resulted in residents prescribing generic rather than brand name statins for lipid-lowering therapy.;Limitations Small sample, single institution study, and cross-sectional design reduce the ability to generalize.;Bottom line Medical school graduation origin and being in the primary care versus categorical track had an impact on statin-prescribing practices.;Introduction Health care costs in the United States were $2.6 trillion in 2010 and are predicted to rise to $4.6 trillion by 2020.1 As a result, there have been calls to incorporate cost awareness into graduate medical education.2,3 Past efforts to teach residents about costs focused mainly on the inpatient setting,4 and we know relatively little about factors driving resource utilization in residency.5,6 The limited information available about the drivers of resident ordering behavior may be 1 reason why educational interventions to improve cost-effective care among residents have not been successful.7,8 To better understand physician resource utilization patterns as they develop during medical training, we decided to focus on 1 of the “Top 5” practices that may be overused in internal medicine. The Top 5 list for internal medicine was developed in 2011 by the National Physician Alliance.9 This initiative later morphed into the American Board of Internal Medicine's Choosing Wisely campaign.10 The Top 5 list for internists included a recommendation to use generic statins rather than brand name statins when initiating lipid-lowering therapy.11,12 In 2009, brand name statin prescribing was estimated to account for $5.8 billion in annual costs.13 This study was designed to address 2 questions: (1) Was there variation in brand name versus generic statin prescribing when initiating cholesterol-lowering therapy by residents in an urban academic medical center? and (2) What resident characteristics were associated with higher rates of brand name statin prescribing?;Methods We performed a retrospective, cross-sectional analysis of statin prescribing by internal medicine residents at Weill Cornell Internal Medicine Associates—the resident and attending practice of the New York Presbyterian/Weill Cornell internal medicine residency program. We obtained data from the practice's electronic health record for all patient encounters between July 1, 2010, and June 30, 2011 (including office visits, telephone encounters, and order-only encounters), where a statin was prescribed for a patient not previously receiving statin therapy. We selected this time interval because it predated generic availability of atorvastatin; therefore, all prescriptions for atorvastatin and rosuvastatin were for brand name Lipitor and Crestor, respectively. The study period also predated the US Food and Drug Administration's announcement about increased risk of muscle injury with high-dose simvastatin in June 2011. Because we were interested in residents' initial choice of statin, we only included encounters in which the resident initiated statin therapy for a patient who was already established in the practice (for any indication). We excluded encounters in which the statin was refilled because this may not have reflected resident's choice of medication. We also excluded encounters for new patients because we were unable to distinguish whether the patient came to that visit already taking a statin (started by a previous doctor), with the resident just continuing the prior medication, or whether the resident initiated new statin therapy for the patient. Prescriptions that were later changed or discontinued (eg, if the patient or insurance company requested a change) were included in the analysis because our aim was to study initial prescribing behavior by the resident rather than the final statin obtained by the patie
机译:众所周知,人们呼吁提高居民对其治疗决定的成本影响的认识。新近的一项研究评估了居民和遭遇水平上的因素,导致居民开出了通用而非品牌的他汀类药物用于降脂治疗局限性;小样本,单一机构研究和横断面设计降低了概括的能力。;底线医学院毕业的起源和处于初级保健与分类的关系对他汀类药物的处方操作产生了影响。 2010年,美国的医疗费用为2.6万亿美元,预计到2020.1年将增至4.6万亿美元。结果,人们呼吁将费用意识纳入研究生医学教育中。2,3过去向居民讲授费用的工作主要集中在住院环境4,我们对居民资源利用的影响因素知之甚少5,6。关于居民订购行为的驱动因素可能是改善居民间成本效益医疗的教育干预措施未获得成功的原因之一。7,8为了更好地了解医生在医学培训期间发展的资源利用模式,我们决定重点关注可能在内科医学中过度使用的“前5名”实践中的1种。内科医学前五名名单由国家医师联盟于2011年制定。9此倡议后来演变为美国内科医学委员会的“明智选择”运动。10内科医师前五名名单包括建议使用仿制他汀类药物而非品牌药开始降脂治疗时使用他汀类药物命名。11,122009年,处方他汀类药物的处方药估计每年花费58亿美元。13本研究旨在解决两个问题:(1)品牌名称与在城市学术医学中心的居民中开始降胆固醇治疗时,应使用普通的他汀类药物? (2)哪些居民特征与较高的品牌他汀类药物处方率相关?;方法我们对Weill Cornell Internal Medicine Associates的内科医学居民进行了回顾性,横断面分析,他汀类药物的处方和使用实践纽约长老会/威尔·康奈尔大学内部医学住院医师课程。我们从该诊所的电子健康记录中获取了2010年7月1日至2011年6月30日之间所有患者遭遇的数据(包括办公室就诊,电话经历和仅订购的经历),其中以前未接受过该药的患者处方了他汀类药物他汀类药物疗法。我们选择此时间间隔是因为它早于阿托伐他汀的通用药效。因此,所有阿托伐他汀和瑞舒伐他汀的处方分别以商品名Lipitor和Crestor命名。研究期还早于2011年6月美国食品和药物管理局宣布高剂量辛伐他汀引起肌肉损伤的风险。由于我们对居民最初选择他汀类药物感兴趣,因此我们仅包括居民开始使用他汀类药物治疗的遭遇适用于已在实践中确定的患者(用于任何适应症)。我们排除了补充他汀类药物的情况,因为这可能并未反映出居民对药物的选择。我们还排除了新患者的遭遇,因为我们无法区分患者来访时是否已经服用他汀类药物(由先前的医生开始),而患者只是继续服用之前的药物,或者患者是否针对以下原因开始了新的他汀类药物治疗:患者。分析中包括后来更改或中止的处方(例如,如果患者或保险公司要求更改),因为我们的目的是研究居民最初的处方行为,而不是患者获得的最终他汀类药物

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