O011. Patients with “prolonged aura” do not show clinical or demographic differences from the patients with “typical aura”

摘要

A recent systematic review of the duration of migraine aura reported that aura symptoms may last longer than one hour in a significant proportion of patients[1]. Here we investigated in a prospective diary-aided study whether patients with a 鈥減rolonged aura鈥?(PA - an aura in which there is at least one symptom lasting for more than one hour) are different from the patients with a 鈥渢ypical aura鈥?(TA). We recruited 176 consecutive patients affected by migraine with aura at the Headache Centres of Pavia and Trondheim. The study received approval by the local Ethics Committees. All patients signed an informed consent form. Fifty-four patients completed the study recording prospectively the characteristics of three consecutive attacks in an ad hoc aura diary that included the time of onset and the end of each aura symptom and the headache. We also collected demographic and clinical variables of each patient including age, gender, presence of headache associated with aura, frequency of migraine with aura attacks, age at onset of migraine with aura, duration of illness, co-occurrence of migraine without aura or tension-type headache, age of migraine without aura onset, use of a migraine preventive therapy, family history for migraine with aura and white matter lesions at MRI in the analysis. We performed an analysis to evaluate if there was any demographic or clinical variable associated with having suffered from at least one PA out of three attacks. For the first time we demonstrate that patients with 鈥減rolonged aura鈥?have no demographic and clinical differences with patients with 鈥渢ypical aura鈥? These data support the need to review the ICHD criteria for migraine with aura. Written informed consent to publication was obtained from the patient(s). None.